{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(2)"],"submitter":["Lo S"],"pubmed_abstract":["Multidrug-resistant <i>Enterobacterales</i>, including carbapenemase producers, are currently spreading in health care facilities and the community. The Bichat Claude Bernard hospital in Paris faced a prolonged NDM-producing <i>Enterobacterales</i> (NDM-CPE) outbreak. Whole-genome sequencing (WGS) was performed on all isolated NDM-CPE to evaluate its benefits for outbreak surveillance and comprehension. All NDM-CPE isolates collected during the outbreak period (August 2016 to January 2018) were sequenced using the Illumina NextSeq platform. Gene content and core genomes were compared. Genomics results underwent epidemiological analysis which classified NDM-CPE cases as imported (positive sample during the 48 h after admission), hospital acquired, or uncertain. Over the epidemic period, 61 "],"journal":["Microbiology spectrum"],"pagination":["e0228721"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9045244"],"repository":["biostudies-literature"],"pubmed_title":["Simultaneous Hospital Outbreaks of New Delhi Metallo-β-Lactamase-Producing <i>Enterobacterales</i> Unraveled Using Whole-Genome Sequencing."],"pmcid":["PMC9045244"],"pubmed_authors":["Lo S","d'Humieres C","Ruppe E","Goldstein V","Wicky PH","Lucet JC","Lolom I","Rondinaud E","Armand-Lefevre L","Bunel-Gourdy V","Petitjean M","Tran Dinh A"],"additional_accession":[]},"is_claimable":false,"name":"Simultaneous Hospital Outbreaks of New Delhi Metallo-β-Lactamase-Producing <i>Enterobacterales</i> Unraveled Using Whole-Genome Sequencing.","description":"Multidrug-resistant <i>Enterobacterales</i>, including carbapenemase producers, are currently spreading in health care facilities and the community. The Bichat Claude Bernard hospital in Paris faced a prolonged NDM-producing <i>Enterobacterales</i> (NDM-CPE) outbreak. Whole-genome sequencing (WGS) was performed on all isolated NDM-CPE to evaluate its benefits for outbreak surveillance and comprehension. All NDM-CPE isolates collected during the outbreak period (August 2016 to January 2018) were sequenced using the Illumina NextSeq platform. Gene content and core genomes were compared. Genomics results underwent epidemiological analysis which classified NDM-CPE cases as imported (positive sample during the 48 h after admission), hospital acquired, or uncertain. Over the epidemic period, 61 ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-06-10T06:20:24.77Z","creation":"2025-04-04T09:20:41.036Z"},"accession":"S-EPMC9045244","cross_references":{"pubmed":["35311539"],"doi":["10.1128/spectrum.02287-21"]}}