biostudies-literatureUnknown53Thakar A<i>Introduction</i> During the COVID-19 pandemic in India, Ayurvedic medication (<i>Guduchi Ghanavati,</i> GG) was prescribed by Ayurveda physicians for prevention and management. This study aimed to evaluate the prophylactic effect of GG in individuals with moderate to very high risk of SARS-CoV-2. <i>Methods</i> A multicenter, controlled, quasi-experimental, before-and-after study was conducted on individuals at moderate to very high risk of SARS-COV-2 exposure. In the intervention group (<i>n</i> = 15,992), participants received GG 1 g daily for 28 days in conjunction with standard preventive guidelines (SPG), while in the control group (<i>n</i> = 4953), participants were asked to follow SPG only. Outcomes were the incidence of COVID-19, perceived immune status, quality of life, and saEuropean journal of integrative medicine102131https://www.ebi.ac.uk/biostudies/studies/S-EPMC9047434biostudies-literature<i>Guduchi Ghanavati</i> (Ayurveda medication) improves the perceived immunity in individuals at risk of SARS-CoV-2: A Multicentred, controlled, before-and-after study.PMC9047434Bhinde SJain NPanara KRaghavani HJani DDodia RVyas JBhatt PSalve RShah HThakar AGoyal MRuparel SChaudhari SKalsariya BPatel Ffalse<i>Guduchi Ghanavati</i> (Ayurveda medication) improves the perceived immunity in individuals at risk of SARS-CoV-2: A Multicentred, controlled, before-and-after study.<i>Introduction</i> During the COVID-19 pandemic in India, Ayurvedic medication (<i>Guduchi Ghanavati,</i> GG) was prescribed by Ayurveda physicians for prevention and management. This study aimed to evaluate the prophylactic effect of GG in individuals with moderate to very high risk of SARS-CoV-2. <i>Methods</i> A multicenter, controlled, quasi-experimental, before-and-after study was conducted on individuals at moderate to very high risk of SARS-COV-2 exposure. In the intervention group (<i>n</i> = 15,992), participants received GG 1 g daily for 28 days in conjunction with standard preventive guidelines (SPG), while in the control group (<i>n</i> = 4953), participants were asked to follow SPG only. Outcomes were the incidence of COVID-19, perceived immune status, quality of life, and sa2022-01-01T00:00:00Z2022 Aug2026-05-30T14:32:52.871Z2022-07-10T00:43:53.081ZS-EPMC90474343550601210.1016/j.eujim.2022.102131