{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Beissbarth J"],"pubmed_abstract":["<h4>Introduction</h4>Otitis media (OM) is a common childhood illness, often resolving without intervention and acute and long-term complications are rare. However, Australian Aboriginal and Torres Strait Islander infants and children experience a high burden of OM and are at high risk of complications (tympanic membrane perforation and chronic infections). Bacterial OM is commonly associated with <i>Streptococcus pneumoniae</i>, non-typeable <i>Haemophilus influenzae</i>, and <i>Moraxella catarrhalis</i>. BIGDATA is a data asset combining over 25 years of microbiology and OM surveillance research from the Ear Health Research Program at Menzies School of Health Research (Northern Territory, Australia), including 11 randomized controlled trials, four cohort studies, eight surveys in over 30 "],"journal":["Frontiers in pediatrics"],"pagination":["804373"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9047683"],"repository":["biostudies-literature"],"pubmed_title":["BIGDATA: A Protocol to Create and Extend a 25-Year Clinical Trial and Observational Data Asset to Address Key Knowledge Gaps in Otitis Media and Hearing Loss in Australian Aboriginal and Non-Aboriginal Children."],"pmcid":["PMC9047683"],"pubmed_authors":["Cheng AC","Morris PS","Beissbarth J","Leach AJ","Smith-Vaughan HC"],"additional_accession":[]},"is_claimable":false,"name":"BIGDATA: A Protocol to Create and Extend a 25-Year Clinical Trial and Observational Data Asset to Address Key Knowledge Gaps in Otitis Media and Hearing Loss in Australian Aboriginal and Non-Aboriginal Children.","description":"<h4>Introduction</h4>Otitis media (OM) is a common childhood illness, often resolving without intervention and acute and long-term complications are rare. However, Australian Aboriginal and Torres Strait Islander infants and children experience a high burden of OM and are at high risk of complications (tympanic membrane perforation and chronic infections). Bacterial OM is commonly associated with <i>Streptococcus pneumoniae</i>, non-typeable <i>Haemophilus influenzae</i>, and <i>Moraxella catarrhalis</i>. BIGDATA is a data asset combining over 25 years of microbiology and OM surveillance research from the Ear Health Research Program at Menzies School of Health Research (Northern Territory, Australia), including 11 randomized controlled trials, four cohort studies, eight surveys in over 30 ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T00:43:12.297Z","creation":"2025-04-07T11:45:41.021Z"},"accession":"S-EPMC9047683","cross_references":{"pubmed":["35498792"],"doi":["10.3389/fped.2022.804373"]}}