{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li F"],"funding":["Chongqing University of Education","Chongqing Municipal Education Commission","Program for Innovation Team Building at Institutions of Higher Education in Chongqing"],"pagination":["1-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9048285"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(1)"],"pubmed_abstract":["This study was conducted to investigate the preventative effect of <i>Lactobacillus fermentum</i> HFY06 on carbon tetrachloride (CCl<sub>4</sub>)-induced liver injury in Kunming mice. Mice were treated with HFY06, then liver damage was induced using CCl<sub>4</sub>. Evaluation indicators included the activities of aspartate aminotransferase (AST), triglycerides (TG), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and malondialdehyde (MDA) in serum; cytokines levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in serum; and related gene expressions of nuclear factor-κB (NF-κB), TNF-α, cyclooxygenase-2 (COX-2), copper/zinc superoxide dismutase (Cu/Zn-SOD), manganese superoxide dismutase (Mn-SOD), and catalase (CAT). Liver tissue was stained "],"journal":["RSC advances"],"pubmed_title":["<i>Lactobacillus fermentum</i> HFY06 reduced CCl<sub>4</sub>-induced hepatic damage in Kunming mice."],"pmcid":["PMC9048285"],"funding_grant_id":["CXTDX201601040","KY201919C","KJZD-K201901601"],"pubmed_authors":["Li W","Zhong Q","Li F","Liao W","Lu DY","Tan F","Zhao X"],"additional_accession":[]},"is_claimable":false,"name":"<i>Lactobacillus fermentum</i> HFY06 reduced CCl<sub>4</sub>-induced hepatic damage in Kunming mice.","description":"This study was conducted to investigate the preventative effect of <i>Lactobacillus fermentum</i> HFY06 on carbon tetrachloride (CCl<sub>4</sub>)-induced liver injury in Kunming mice. Mice were treated with HFY06, then liver damage was induced using CCl<sub>4</sub>. Evaluation indicators included the activities of aspartate aminotransferase (AST), triglycerides (TG), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and malondialdehyde (MDA) in serum; cytokines levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in serum; and related gene expressions of nuclear factor-κB (NF-κB), TNF-α, cyclooxygenase-2 (COX-2), copper/zinc superoxide dismutase (Cu/Zn-SOD), manganese superoxide dismutase (Mn-SOD), and catalase (CAT). Liver tissue was stained ","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Dec","modification":"2025-05-18T12:06:14.762Z","creation":"2025-04-05T20:38:24.811Z"},"accession":"S-EPMC9048285","cross_references":{"pubmed":["35492553"],"doi":["10.1039/c9ra08789c"]}}