biostudies-literatureTurksoy ADalian University of TechnologyTürkiye Bilimsel ve Teknolojik Araştirma Kurumu9182-9186https://www.ebi.ac.uk/biostudies/studies/S-EPMC9050071biostudies-literatureUnknown10(16)Controlled generation of singlet oxygen is very important due to its involvement in scheduled cellular maintenance processes and therapeutic potential. As a consequence, precise manipulation of singlet oxygen release rates under mild conditions, is crucial. In this work, a cross-linked polyacrylate, and a polydimethylsiloxane elastomer incorporating anthracene-endoperoxide modules with chain extensions at the 9,10-positions were synthesized. We now report that on mechanical agitation in cryogenic ball mill, fluorescence emission due to anthracene units in the PMA (polymethacrylate) polymer is enhanced, with a concomitant generation of singlet oxygen as proved by detection with a selective probe. The PDMS (polydimethylsiloxane) elastomer with the anthracene endoperoxide mechanophore, is alsRSC advancesMechanochemical generation of singlet oxygen.PMC9050071DUT18RC(3)0622210-EAydonat SCanyurt MTurksoy ABeduk TYildiz DBaytekin BAkkaya EUfalseMechanochemical generation of singlet oxygen.Controlled generation of singlet oxygen is very important due to its involvement in scheduled cellular maintenance processes and therapeutic potential. As a consequence, precise manipulation of singlet oxygen release rates under mild conditions, is crucial. In this work, a cross-linked polyacrylate, and a polydimethylsiloxane elastomer incorporating anthracene-endoperoxide modules with chain extensions at the 9,10-positions were synthesized. We now report that on mechanical agitation in cryogenic ball mill, fluorescence emission due to anthracene units in the PMA (polymethacrylate) polymer is enhanced, with a concomitant generation of singlet oxygen as proved by detection with a selective probe. The PDMS (polydimethylsiloxane) elastomer with the anthracene endoperoxide mechanophore, is als2020-01-01T00:00:00Z2020 Mar2025-04-04T08:21:00.713Z2025-02-18T23:21:56.26ZS-EPMC90500713549722910.1039/d0ra00831a