biostudies-literatureManickam SCouncil of Scientific and Industrial Research, India11791-11799https://www.ebi.ac.uk/biostudies/studies/S-EPMC9050552biostudies-literatureUnknown10(20)Herein, the turn-off fluorescence sensor of 2-((4'-(7,8,13,14-tetrahydrodibenzo[<i>a</i>,<i>i</i>]phenanthridin-5-yl)-[1,1'-biphenyl]-4-yl)methylene)malanonitrile (7) was developed for the recognition of CN^- ions and studied using different spectroscopic techniques. The selective recognition of CN^- ions by 7 was investigated <i>via</i> UV-vis spectroscopy and fluorescence studies in acetonitrile solvent, which exhibited an obvious color change from orange to colorless under 365 UV light. The sensor compound 7 possesses a high binding constant (<i>K</i> _a) for CN^- ions in the order of 5.22 × 10⁶ M^-1. The results from the interference studies revealed that probe 7 shows high sensing selectivity and sensitivity for CN<sup>-</suRSC advancesHighly sensitive turn-off fluorescent detection of cyanide in aqueous medium using dicyanovinyl-substituted phenanthridine fluorophore.PMC905055209/844(0051)/2018 EMR-IManickam SIyer SKfalseHighly sensitive turn-off fluorescent detection of cyanide in aqueous medium using dicyanovinyl-substituted phenanthridine fluorophore.Herein, the turn-off fluorescence sensor of 2-((4'-(7,8,13,14-tetrahydrodibenzo[<i>a</i>,<i>i</i>]phenanthridin-5-yl)-[1,1'-biphenyl]-4-yl)methylene)malanonitrile (7) was developed for the recognition of CN^- ions and studied using different spectroscopic techniques. The selective recognition of CN^- ions by 7 was investigated <i>via</i> UV-vis spectroscopy and fluorescence studies in acetonitrile solvent, which exhibited an obvious color change from orange to colorless under 365 UV light. The sensor compound 7 possesses a high binding constant (<i>K</i> _a) for CN^- ions in the order of 5.22 × 10⁶ M^-1. The results from the interference studies revealed that probe 7 shows high sensing selectivity and sensitivity for CN<sup>-</su2020-01-01T00:00:00Z2020 Mar2025-04-25T22:56:15.48Z2025-04-06T09:15:05.645ZS-EPMC90505523549661010.1039/d0ra00623h