biostudies-literatureUnknown10(22)Szafraniec AThis paper presents the synthesis of a coumarin derivative of resorcin[4]arene (1) using a cascade thermolysis/Michael reaction. The influence of the hydrogen bonding system on the conformational rigidity and cyclochirality of the coumarin derivative of resorcin[4]arene was discussed; these properties depended on the proton-donor-acceptor properties of the solvent. Significant differences, which depended on the environment, in the coumarin derivative of resorcin[4]arene fluorescence were observed and discussed.RSC advances12747-12753https://www.ebi.ac.uk/biostudies/studies/S-EPMC9051107biostudies-literatureSynthesis of a coumarin derivative of resorcin[4]arene with solvent-controlled chirality.PMC9051107Iwanek WSzafraniec AfalseSynthesis of a coumarin derivative of resorcin[4]arene with solvent-controlled chirality.This paper presents the synthesis of a coumarin derivative of resorcin[4]arene (1) using a cascade thermolysis/Michael reaction. The influence of the hydrogen bonding system on the conformational rigidity and cyclochirality of the coumarin derivative of resorcin[4]arene was discussed; these properties depended on the proton-donor-acceptor properties of the solvent. Significant differences, which depended on the environment, in the coumarin derivative of resorcin[4]arene fluorescence were observed and discussed.2020-01-01T00:00:00Z2020 Mar2025-04-19T00:40:36.827Z2025-04-07T11:41:48.48ZS-EPMC90511073549212610.1039/d0ra00368a