{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wickham RJ"],"funding":["NIMH NIH HHS"],"pagination":["A28-A39"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9053429"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["Course-based undergraduate research experiences (CUREs) are increasingly common approaches to provide students with authentic laboratory experiences. Typically, CUREs are semester-long, in-person experiences that can be financially and time prohibitive for some institutions, faculty, and students. Here, we developed a short-duration, fully-online CURE, the Spine Lab, to provide an opportunity for students to conduct original research. In this CURE, we focused on synaptic spines in the mammalian brain; synapses are the unit structure that functions in rapid information processing. The students worked together in pairs and as a class to analyze cortical neuron spine density and structural morphology changes between a mouse line with learning impairments (forebrain-specific β-catenin knockout"],"journal":["Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience"],"pubmed_title":["The Spine Lab: A Short-Duration, Fully-Remote Course-Based Undergraduate Research Experience."],"pmcid":["PMC9053429"],"funding_grant_id":["R01 MH106623"],"pubmed_authors":["Jacob MH","Genne-Bacon EA","Wickham RJ"],"additional_accession":[]},"is_claimable":false,"name":"The Spine Lab: A Short-Duration, Fully-Remote Course-Based Undergraduate Research Experience.","description":"Course-based undergraduate research experiences (CUREs) are increasingly common approaches to provide students with authentic laboratory experiences. Typically, CUREs are semester-long, in-person experiences that can be financially and time prohibitive for some institutions, faculty, and students. Here, we developed a short-duration, fully-online CURE, the Spine Lab, to provide an opportunity for students to conduct original research. In this CURE, we focused on synaptic spines in the mammalian brain; synapses are the unit structure that functions in rapid information processing. The students worked together in pairs and as a class to analyze cortical neuron spine density and structural morphology changes between a mouse line with learning impairments (forebrain-specific β-catenin knockout","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-04T09:10:17.988Z","creation":"2025-02-19T03:24:55.745Z"},"accession":"S-EPMC9053429","cross_references":{"pubmed":["35540947"]}}