biostudies-literatureAnuar NSInstitut Pengurusan dan Pemantauan Penyelidikan, Universiti Malaya17336-17344https://www.ebi.ac.uk/biostudies/studies/S-EPMC9053441biostudies-literatureUnknown10(29)A platinum-silver graphene (Pt-Ag/Gr) nanocomposite modified electrode was fabricated for the electrochemical detection of dopamine (DA). Electrochemical studies of the Pt-Ag/Gr nanocomposite towards DA detection were performed by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CV analysis showed that Pt-Ag/Gr/GCE had enhanced electrocatalytic activity towards DA oxidation due to the synergistic effects between the platinum-silver nanoparticles and graphene. The DPV results showed that the modified sensor demonstrated a linear concentration range between 0.1 and 60 μM with a limit of detection of 0.012 μM. The Pt-Ag/Gr/GCE presented satisfactory results for reproducibility, stability and selectivity. The prepared sensor also showed acceptable recoveries for a real sample study.RSC advancesA dopamine electrochemical sensor based on a platinum-silver graphene nanocomposite modified electrode.PMC9053441PG093-2015BAnuar NSShalauddin MBasirun WJAkhter SfalseA dopamine electrochemical sensor based on a platinum-silver graphene nanocomposite modified electrode.A platinum-silver graphene (Pt-Ag/Gr) nanocomposite modified electrode was fabricated for the electrochemical detection of dopamine (DA). Electrochemical studies of the Pt-Ag/Gr nanocomposite towards DA detection were performed by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CV analysis showed that Pt-Ag/Gr/GCE had enhanced electrocatalytic activity towards DA oxidation due to the synergistic effects between the platinum-silver nanoparticles and graphene. The DPV results showed that the modified sensor demonstrated a linear concentration range between 0.1 and 60 μM with a limit of detection of 0.012 μM. The Pt-Ag/Gr/GCE presented satisfactory results for reproducibility, stability and selectivity. The prepared sensor also showed acceptable recoveries for a real sample study.2020-01-01T00:00:00Z2020 Apr2025-04-29T11:01:26.4Z2025-04-06T19:45:45.655ZS-EPMC90534413552147710.1039/c9ra11056a