{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(40)"],"submitter":["Wang YD"],"pubmed_abstract":["Isochaetoglobosin D<sub>b</sub> is a new chaetoglobosin possessing a unique 3,4-substituted pyrrole ring isolated and named by Qiu <i>et al.</i>, and it is different from any one of the 14 sub-types in the macrocyclic ring of chaetoglobosins classified in our previous work. Its chemical shift values, coupling constants and biosynthetic consideration implied that the proposed structure of isochaetoglobosin D<sub>b</sub> was incorrect. In this report, based on detailed NMR data analysis together with biosynthetic consideration, the structure of isochaetoglobosin D<sub>b</sub> is suggested to be revised to that of penochalasin C. The NMR spectra of penochalasin C measured in the same solvent (DMSO-<i>d</i> <sub>6</sub>) as that of isochaetoglobosin D<sub>b</sub> supported the above conclusion"],"journal":["RSC advances"],"pagination":["23969-23974"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9055075"],"repository":["biostudies-literature"],"pubmed_title":["Revision of the structure of isochaetoglobosin D<sub>b</sub> based on NMR analysis and biosynthetic consideration."],"pmcid":["PMC9055075"],"pubmed_authors":["Shen L","Ding G","Tan XM","Chen L","Wang YD","Wei ZQ","Li YY"],"additional_accession":[]},"is_claimable":false,"name":"Revision of the structure of isochaetoglobosin D<sub>b</sub> based on NMR analysis and biosynthetic consideration.","description":"Isochaetoglobosin D<sub>b</sub> is a new chaetoglobosin possessing a unique 3,4-substituted pyrrole ring isolated and named by Qiu <i>et al.</i>, and it is different from any one of the 14 sub-types in the macrocyclic ring of chaetoglobosins classified in our previous work. Its chemical shift values, coupling constants and biosynthetic consideration implied that the proposed structure of isochaetoglobosin D<sub>b</sub> was incorrect. In this report, based on detailed NMR data analysis together with biosynthetic consideration, the structure of isochaetoglobosin D<sub>b</sub> is suggested to be revised to that of penochalasin C. The NMR spectra of penochalasin C measured in the same solvent (DMSO-<i>d</i> <sub>6</sub>) as that of isochaetoglobosin D<sub>b</sub> supported the above conclusion","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jun","modification":"2025-04-18T15:44:32.298Z","creation":"2024-11-14T03:49:33.131Z"},"accession":"S-EPMC9055075","cross_references":{"pubmed":["35517363"],"doi":["10.1039/d0ra04108d"]}}