{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Qin L"],"funding":["Department of Science and Technology of Sichuan Province"],"pagination":["28397-28407"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9055648"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(47)"],"pubmed_abstract":["Porous β-tricalcium phosphate (β-Ca<sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>, β-TCP) scaffolds are widely applied in the field of bone tissue engineering due to their nontoxicity, degradability, biocompatibility, and osteoinductivity. However, poor compressive strength and a lack of antibacterial properties have hindered their clinical application. In order to address these disadvantages, graphene (G) and silver nanoparticles were introduced into β-TCP through a two-step method. In the synthesis process, G-β-TCP was prepared <i>via</i> an <i>in situ</i> synthesis method, and then silver nanoparticles and HAp particles were coated on the surface of the G-β-TCP scaffold in an orderly fashion using dopamine as a binder. From the results of characterization, when the content of graphene was 1 w"],"journal":["RSC advances"],"pubmed_title":["The preparation of a difunctional porous β-tricalcium phosphate scaffold with excellent compressive strength and antibacterial properties."],"pmcid":["PMC9055648"],"funding_grant_id":["2019YJ0141"],"pubmed_authors":["Yi J","Kenan X","Qin L","Lu X","Xuefei L","Li L"],"additional_accession":[]},"is_claimable":false,"name":"The preparation of a difunctional porous β-tricalcium phosphate scaffold with excellent compressive strength and antibacterial properties.","description":"Porous β-tricalcium phosphate (β-Ca<sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>, β-TCP) scaffolds are widely applied in the field of bone tissue engineering due to their nontoxicity, degradability, biocompatibility, and osteoinductivity. However, poor compressive strength and a lack of antibacterial properties have hindered their clinical application. In order to address these disadvantages, graphene (G) and silver nanoparticles were introduced into β-TCP through a two-step method. In the synthesis process, G-β-TCP was prepared <i>via</i> an <i>in situ</i> synthesis method, and then silver nanoparticles and HAp particles were coated on the surface of the G-β-TCP scaffold in an orderly fashion using dopamine as a binder. From the results of characterization, when the content of graphene was 1 w","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-04-04T21:31:28.428Z","creation":"2024-10-15T07:24:47.057Z"},"accession":"S-EPMC9055648","cross_references":{"pubmed":["35519120"],"doi":["10.1039/d0ra02388d"]}}