{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen X"],"funding":["the National Key Research and Development Program of China, Stem Cell and Translational Research","the Key Scientific and Technological Program of Guangzhou City","the Key Scientific and Technological Projects of Guangdong Province","National Natural Science Foundation of China","The Strategic Priority Research Program of the Chinese Academy of Sciences","The National Key Research and Development Program of China, Stem Cell and Translational Research","the National Natural Science Foundation of China"],"pagination":["e13141"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9055891"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["55(4)"],"pubmed_abstract":["Mesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self-renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources or each individual have great differences in their transcriptomic signatures, differentiation potential and biological functions. Therefore, there is an urgent need for consensus standard for the quality control and technical specifications of MSCs. 'Human Mesenchymal Stem Cells' is the latest set of guidelines on hMSC in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. This standard specifies the te"],"journal":["Cell proliferation"],"pubmed_title":["Human mesenchymal stem cells."],"pmcid":["PMC9055891"],"funding_grant_id":["2018YFA0108400","XDA16040502","201803040011","XDA16040501","2019B020235002","2019B020234001","2019B020236004","XDA16040504","2018YFA0107203","81730005","31771616","2018YFE0204400","81970109","2017YFA0105501"],"pubmed_authors":["Wu J","Peng Y","Hu S","Na T","Hao J","Huang J","Cao J","Li Q","Zhu H","Zhao T","Yu J","Wang L","Fu B","Wu Z","Ma A","Zhang Y","Zhou B","Liang L","Chen X","Wang Y","Wei J","Zhou J","Xiang AP"],"additional_accession":[]},"is_claimable":false,"name":"Human mesenchymal stem cells.","description":"Mesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self-renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources or each individual have great differences in their transcriptomic signatures, differentiation potential and biological functions. Therefore, there is an urgent need for consensus standard for the quality control and technical specifications of MSCs. 'Human Mesenchymal Stem Cells' is the latest set of guidelines on hMSC in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. This standard specifies the te","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-06-04T07:58:49.853Z","creation":"2025-04-25T18:03:55.513Z"},"accession":"S-EPMC9055891","cross_references":{"pubmed":["34936710"],"doi":["10.1111/cpr.13141"]}}