{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["181(5)"],"submitter":["Raffaeli G"],"pubmed_abstract":["Fresh frozen plasma (FFP) is largely misused in the neonatal setting. The aim of the study is to evaluate the impact of a Thromboelastography (TEG)-based Quality Improvement (QI) project on perioperative FFP use and neonatal outcomes. Retrospective pre-post implementation study in a level-III NICU including all neonates undergoing major non-cardiac surgery before (01-12/2017) and after (01-12/2019) the intervention. In 2018, the intervention included the following: (1) Training on TEG, (2) Implementation of TEG, and (3) Algorithm for TEG-directed FFP administration in surgical neonates. We compared pre- vs post-intervention patient characteristics, hemostasis, and clinical management. Linear and logistic regression models were used to evaluate the impact of the project on main outcomes. We"],"journal":["European journal of pediatrics"],"pagination":["2173-2182"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9056479"],"repository":["biostudies-literature"],"pubmed_title":["Optimizing fresh-frozen plasma transfusion in surgical neonates through thromboelastography: a quality improvement study."],"pmcid":["PMC9056479"],"pubmed_authors":["Ghirardello S","Manzoni F","Macchini F","Napolitano L","Raffaeli G","Cavallaro G","Amelio GS","Pesenti N","Mosca F","Cortesi V","Gulden S"],"additional_accession":[]},"is_claimable":false,"name":"Optimizing fresh-frozen plasma transfusion in surgical neonates through thromboelastography: a quality improvement study.","description":"Fresh frozen plasma (FFP) is largely misused in the neonatal setting. The aim of the study is to evaluate the impact of a Thromboelastography (TEG)-based Quality Improvement (QI) project on perioperative FFP use and neonatal outcomes. Retrospective pre-post implementation study in a level-III NICU including all neonates undergoing major non-cardiac surgery before (01-12/2017) and after (01-12/2019) the intervention. In 2018, the intervention included the following: (1) Training on TEG, (2) Implementation of TEG, and (3) Algorithm for TEG-directed FFP administration in surgical neonates. We compared pre- vs post-intervention patient characteristics, hemostasis, and clinical management. Linear and logistic regression models were used to evaluate the impact of the project on main outcomes. We","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-26T15:15:59.58Z","creation":"2025-04-06T14:52:31.758Z"},"accession":"S-EPMC9056479","cross_references":{"pubmed":["35211816"],"doi":["10.1007/s00431-022-04427-6"]}}