{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(58)"],"submitter":["Oeser P"],"pubmed_abstract":["We studied the reactions of vinyl phosphates and vinyl phosphordiamidates containing an ester functional group with organometallic reagents. We found that the functionalized vinyl phosphates were smoothly converted into tri- and tetrasubstituted buta-1,3-dienes <i>via</i> the reaction with aryllithium reagents. Moreover, the vinyl phosphordiamidates were converted into α,β-unsaturated ketones using Grignard reagents. Based on the performed experiments, we proposed a reaction mechanism, which was confirmed by means of the isolation of key intermediates."],"journal":["RSC advances"],"pagination":["35109-35120"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9056830"],"repository":["biostudies-literature"],"pubmed_title":["Formation of trisubstituted buta-1,3-dienes and α,β-unsaturated ketones <i>via</i> the reaction of functionalized vinyl phosphates and vinyl phosphordiamidates with organometallic reagents."],"pmcid":["PMC9056830"],"pubmed_authors":["Dvorakova H","Oeser P","Koudelka J","Tobrman T"],"additional_accession":[]},"is_claimable":false,"name":"Formation of trisubstituted buta-1,3-dienes and α,β-unsaturated ketones <i>via</i> the reaction of functionalized vinyl phosphates and vinyl phosphordiamidates with organometallic reagents.","description":"We studied the reactions of vinyl phosphates and vinyl phosphordiamidates containing an ester functional group with organometallic reagents. We found that the functionalized vinyl phosphates were smoothly converted into tri- and tetrasubstituted buta-1,3-dienes <i>via</i> the reaction with aryllithium reagents. Moreover, the vinyl phosphordiamidates were converted into α,β-unsaturated ketones using Grignard reagents. Based on the performed experiments, we proposed a reaction mechanism, which was confirmed by means of the isolation of key intermediates.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Sep","modification":"2025-05-29T21:29:13.932Z","creation":"2025-05-29T21:29:13.932Z"},"accession":"S-EPMC9056830","cross_references":{"pubmed":["35515642"],"doi":["10.1039/d0ra07472a"]}}