{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(59)"],"submitter":["Chandra Sau M"],"pubmed_abstract":["The Nakamura reaction using a cationic cobalt(iii) complex, [Cp*Co(CH<sub>3</sub>CN)<sub>3</sub>][SbF<sub>6</sub>]<sub>2</sub> as the catalyst under neutral and aerobic conditions at 110 °C has been described. In solution, the complex is expected to lose a hemilabile acetonitrile ligand to produce a highly electron-deficient cobalt(iii) center, and the Lewis acidic nature of the cobalt center has been exploited for the enolization of the dicarbonyl compounds. The reaction of 1,3-dicarbonyl compounds with alkynes affords the corresponding alkenyl derivative. However, the reaction of phenylacetylene and its derivatives with β-ketoesters affords corresponding terphenyl compounds. Details of the mechanisms of the reactions have been proposed based on <i>in situ</i> LCMS measurements."],"journal":["RSC advances"],"pagination":["36014-36019"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9056990"],"repository":["biostudies-literature"],"pubmed_title":["Addition of 1,3-dicarbonyl compounds to terminal alkynes catalyzed by a cationic cobalt(iii) complex."],"pmcid":["PMC9056990"],"pubmed_authors":["Chandra Sau M","Bhattacharjee M"],"additional_accession":[]},"is_claimable":false,"name":"Addition of 1,3-dicarbonyl compounds to terminal alkynes catalyzed by a cationic cobalt(iii) complex.","description":"The Nakamura reaction using a cationic cobalt(iii) complex, [Cp*Co(CH<sub>3</sub>CN)<sub>3</sub>][SbF<sub>6</sub>]<sub>2</sub> as the catalyst under neutral and aerobic conditions at 110 °C has been described. In solution, the complex is expected to lose a hemilabile acetonitrile ligand to produce a highly electron-deficient cobalt(iii) center, and the Lewis acidic nature of the cobalt center has been exploited for the enolization of the dicarbonyl compounds. The reaction of 1,3-dicarbonyl compounds with alkynes affords the corresponding alkenyl derivative. However, the reaction of phenylacetylene and its derivatives with β-ketoesters affords corresponding terphenyl compounds. Details of the mechanisms of the reactions have been proposed based on <i>in situ</i> LCMS measurements.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Sep","modification":"2024-11-21T02:48:52.71Z","creation":"2024-11-21T02:48:52.71Z"},"accession":"S-EPMC9056990","cross_references":{"pubmed":["35517105"],"doi":["10.1039/d0ra05923d"]}}