biostudies-literatureDurcan EBilimsel Araştirma Projeleri Birimi, Istanbul Üniversitesi236-246https://www.ebi.ac.uk/biostudies/studies/S-EPMC9060072biostudies-literatureUnknown14(4)<h4>Background</h4>The aim of this study was to investigate the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on the glomerulus through the evaluation of podocyturia in patients with diabetic kidney disease (DKD).<h4>Methods</h4>The study population was composed of 40 male patients with type 2 diabetes mellitus; 22 of them received SGLT2i (SGLT2i group), and the others who did not were the control. The DKD-related parameters of patients were monitored before SGLT2i initiation, and then in the third and sixth month of the follow-up period. Patients' demographic, clinical, laboratory, and follow-up data were obtained from medical charts. Microalbuminuria was measured in 24-h urine. The number of podocytes in the urine was determined by immunocytochemical staining of two diffeJournal of diabetesEffects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia.PMC906007233562Saygi HIBakir ASahin SKaraca CDurcan EDincer MTGonen MSSulu COzkan STrabulus SGuzel ESeyahi NKorkmaz OPOzkaya HMfalseEffects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia.<h4>Background</h4>The aim of this study was to investigate the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on the glomerulus through the evaluation of podocyturia in patients with diabetic kidney disease (DKD).<h4>Methods</h4>The study population was composed of 40 male patients with type 2 diabetes mellitus; 22 of them received SGLT2i (SGLT2i group), and the others who did not were the control. The DKD-related parameters of patients were monitored before SGLT2i initiation, and then in the third and sixth month of the follow-up period. Patients' demographic, clinical, laboratory, and follow-up data were obtained from medical charts. Microalbuminuria was measured in 24-h urine. The number of podocytes in the urine was determined by immunocytochemical staining of two diffe2022-01-01T00:00:00Z2022 Apr2025-04-18T13:15:37.671Z2025-04-06T22:49:14.028ZS-EPMC90600723522945810.1111/1753-0407.13261