{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["96"],"submitter":["Dong SJ"],"pubmed_abstract":["<h4>Background</h4>The presence of left atrial/left atrial appendage thrombosis is associated with a higher risk of thromboembolic events in patients with atrial fibrillation. The optimal antithrombotic strategy is not established to date.<h4>Objective</h4>Our aim was to compare the efficacy and safety profile of novel oral anticoagulants with warfarin in the treatment of left atrial/left atrial appendage thrombosis.<h4>Methods</h4>We conducted a systematic search in PubMed, Embase, Cochrane Library, ClinicalTrials.gov, and 3 Chinese databases for all randomized controlled trials and cohort studies (PROSPERO, CRD42021238952) from inception to 7 May 2021. Two authors independently performed the articles selection, data extraction, and quality assessment. The efficacy outcome was the resolut"],"journal":["Current therapeutic research, clinical and experimental"],"pagination":["100670"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9062445"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy and Safety Profile of Novel Oral Anticoagulants in the Treatment of Left Atrial Thrombosis: A Systematic Review and Meta-Analysis."],"pmcid":["PMC9062445"],"pubmed_authors":["Xiao CL","Luo CY","Zhai SD","Han ZL","Dong SJ","Zhang FZ","Li L"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy and Safety Profile of Novel Oral Anticoagulants in the Treatment of Left Atrial Thrombosis: A Systematic Review and Meta-Analysis.","description":"<h4>Background</h4>The presence of left atrial/left atrial appendage thrombosis is associated with a higher risk of thromboembolic events in patients with atrial fibrillation. The optimal antithrombotic strategy is not established to date.<h4>Objective</h4>Our aim was to compare the efficacy and safety profile of novel oral anticoagulants with warfarin in the treatment of left atrial/left atrial appendage thrombosis.<h4>Methods</h4>We conducted a systematic search in PubMed, Embase, Cochrane Library, ClinicalTrials.gov, and 3 Chinese databases for all randomized controlled trials and cohort studies (PROSPERO, CRD42021238952) from inception to 7 May 2021. Two authors independently performed the articles selection, data extraction, and quality assessment. The efficacy outcome was the resolut","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-07-14T14:41:26.549Z","creation":"2024-11-15T12:41:12.241Z"},"accession":"S-EPMC9062445","cross_references":{"pubmed":["35515958"],"doi":["10.1016/j.curtheres.2022.100670"]}}