{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Woods-Hill CZ"],"funding":["NCATS NIH HHS","NIAID NIH HHS","AHRQ HHS","NHLBI NIH HHS"],"pagination":["690-698"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9062771"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["176(7)"],"pubmed_abstract":["<h4>Importance</h4>Blood culture overuse in the pediatric intensive care unit (PICU) can lead to unnecessary antibiotic use and contribute to antibiotic resistance. Optimizing blood culture practices through diagnostic stewardship may reduce unnecessary blood cultures and antibiotics.<h4>Objective</h4>To evaluate the association of a 14-site multidisciplinary PICU blood culture collaborative with culture rates, antibiotic use, and patient outcomes.<h4>Design, setting, and participants</h4>This prospective quality improvement (QI) collaborative involved 14 PICUs across the United States from 2017 to 2020 for the Bright STAR (Testing Stewardship for Antibiotic Reduction) collaborative. Data were collected from each participating PICU and from the Children's Hospital Association Pediatric Hea"],"journal":["JAMA pediatrics"],"pubmed_title":["Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative."],"pmcid":["PMC9062771"],"funding_grant_id":["R18 HS025642","K23 HL151381","K24 AI141580","UL1 TR002538"],"pubmed_authors":["Steffen KM","Fackler JC","Toltzis P","Woods-Hill CZ","Dallefeld S","Hauger SB","Agulnik A","Hysmith ND","Tadphale SD","Smith CM","Colantuoni EA","Foster CB","Thurm C","Schwenk HT","Sandora TJ","Kociolek LK","Wolf J","Clayton JA","Auth MJ","Larsen GY","Xie A","Miller MR","Albert JE","Milstone AM","Bright STAR Authorship Group","Flaherty BF","Ezetendu CP","Lin JC","Nolt D","Kirby AL","Priebe GP","Coffin SE","Koontz DW","Fainberg NA","Voskertchian A","Zerr DM","Linam WM","Newland JG","Bradley E","Hong SJ"],"additional_accession":[]},"is_claimable":false,"name":"Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative.","description":"<h4>Importance</h4>Blood culture overuse in the pediatric intensive care unit (PICU) can lead to unnecessary antibiotic use and contribute to antibiotic resistance. Optimizing blood culture practices through diagnostic stewardship may reduce unnecessary blood cultures and antibiotics.<h4>Objective</h4>To evaluate the association of a 14-site multidisciplinary PICU blood culture collaborative with culture rates, antibiotic use, and patient outcomes.<h4>Design, setting, and participants</h4>This prospective quality improvement (QI) collaborative involved 14 PICUs across the United States from 2017 to 2020 for the Bright STAR (Testing Stewardship for Antibiotic Reduction) collaborative. Data were collected from each participating PICU and from the Children's Hospital Association Pediatric Hea","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2026-06-14T07:48:27.196Z","creation":"2024-11-06T21:32:27.881Z"},"accession":"S-EPMC9062771","cross_references":{"pubmed":["35499841"],"doi":["10.1001/jamapediatrics.2022.1024"]}}