biostudies-literatureAzeem MNankai UniversityNational Natural Science Foundation of China13153-13158https://www.ebi.ac.uk/biostudies/studies/S-EPMC9063740biostudies-literatureUnknown9(23)Coordination polymer based dietary supplement tablets are commonly consumed in our daily life and play an important role in the pharmaceutical industry. To fully understand their tableting process, their mechanical properties need to be comprehensively studied. In this work, the elastic and hydrostatic behaviour of a zinc supplement, zinc glycinate hydrate (Zn[O₂CCH₂NH₂]₂·H₂O), have been studied <i>via</i> density functional theory (DFT) calculations and high-pressure synchrotron powder X-ray diffraction. This material has a pseudo-layered structure and can be successfully exfoliated into nanosheets. The DFT calculated elastic moduli along the principal axes (13.84-36.11 GPa) indicate a significant elastic anisotropy of ZnG as expectedRSC advancesElastic and hydrostatic behaviour of a zinc dietary supplement, zinc glycinate hydrate.PMC90637402157107263196006Gui DLi WPei CAzeem MDong LAsif MLu PfalseElastic and hydrostatic behaviour of a zinc dietary supplement, zinc glycinate hydrate.Coordination polymer based dietary supplement tablets are commonly consumed in our daily life and play an important role in the pharmaceutical industry. To fully understand their tableting process, their mechanical properties need to be comprehensively studied. In this work, the elastic and hydrostatic behaviour of a zinc supplement, zinc glycinate hydrate (Zn[O₂CCH₂NH₂]₂·H₂O), have been studied <i>via</i> density functional theory (DFT) calculations and high-pressure synchrotron powder X-ray diffraction. This material has a pseudo-layered structure and can be successfully exfoliated into nanosheets. The DFT calculated elastic moduli along the principal axes (13.84-36.11 GPa) indicate a significant elastic anisotropy of ZnG as expected2019-01-01T00:00:00Z2019 Apr2025-06-01T02:33:56.232Z2025-06-01T02:33:56.232ZS-EPMC90637403552079510.1039/c9ra00385a