{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Muhammad I"],"funding":["Special Fund for Agro-scientific Research in the Public Interest","Education Department of Jilin Province","National Natural Science Foundation of China"],"pagination":["14758-14765"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9064161"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(26)"],"pubmed_abstract":["Outbreaks of cobweb disease are becoming increasingly prevalent globally, severely affecting the quality and yield of <i>Agaricus bisporus</i>. However, cobweb disease-resistant strains are rare, and little is known regarding the biocontrol management of the disease. Here, we isolated a pathogen from a severe outbreak of cobweb disease on <i>A. bisporus</i> in China and identified it as <i>Cladobotryum mycophilum</i> based on morphological characteristics, rDNA sequences, and pathogenicity tests. We then tested 30 <i>A. bisporus</i> strains for cobweb disease resistance by inoculating with <i>C. mycophilum</i> and evaluated the activity of different botanicals. We found that two wild strains of <i>A. bisporus</i> originating from the Tibetan Plateau in China were resistant to cobweb diseas"],"journal":["RSC advances"],"pubmed_title":["Identification of resistance to cobweb disease caused by <i>Cladobotryum mycophilum</i> in wild and cultivated strains of <i>Agaricus bisporus</i> and screening for bioactive botanicals."],"pmcid":["PMC9064161"],"funding_grant_id":["201503137","31701977"],"pubmed_authors":["Sossah FL","Li Y","Yang Y","Li S","Li D","Fu Y","Muhammad I"],"additional_accession":[]},"is_claimable":false,"name":"Identification of resistance to cobweb disease caused by <i>Cladobotryum mycophilum</i> in wild and cultivated strains of <i>Agaricus bisporus</i> and screening for bioactive botanicals.","description":"Outbreaks of cobweb disease are becoming increasingly prevalent globally, severely affecting the quality and yield of <i>Agaricus bisporus</i>. However, cobweb disease-resistant strains are rare, and little is known regarding the biocontrol management of the disease. Here, we isolated a pathogen from a severe outbreak of cobweb disease on <i>A. bisporus</i> in China and identified it as <i>Cladobotryum mycophilum</i> based on morphological characteristics, rDNA sequences, and pathogenicity tests. We then tested 30 <i>A. bisporus</i> strains for cobweb disease resistance by inoculating with <i>C. mycophilum</i> and evaluated the activity of different botanicals. We found that two wild strains of <i>A. bisporus</i> originating from the Tibetan Plateau in China were resistant to cobweb diseas","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 May","modification":"2026-05-30T14:50:10.824Z","creation":"2022-07-11T20:05:26.062Z"},"accession":"S-EPMC9064161","cross_references":{"pubmed":["35516343"],"doi":["10.1039/c9ra00632j"]}}