biostudies-literatureAmin SGeneralitat de CatalunyaMinisterio de Economía y CompetitividadKempestiftelsernaEuropean Commission14443-14451https://www.ebi.ac.uk/biostudies/studies/S-EPMC9064170biostudies-literatureUnknown9(25)We propose a new facile electrochemical sensing platform for determination of urea, based on a glassy carbon electrode (GCE) modified with nickel cobalt oxide (NiCo₂O₄) nanoneedles. These nanoneedles are used for the first time for highly sensitive determination of urea with the lowest detection limit (1 μM) ever reported for the non-enzymatic approach. The nanoneedles were grown through a simple and low-temperature aqueous chemical method. We characterized the structural and morphological properties of the NiCo₂O₄ nanoneedles by TEM, SEM, XPS and XRD. The bimetallic nickel cobalt oxide exhibits nanoneedle morphology, which results from the self-assembly of nanoparticles. The NiCo₂O₄ nanoneedles are exclusively composed of NRSC advancesA practical non-enzymatic urea sensor based on NiCo₂O₄ nanoneedles.PMC90641702014 SGR 1638GA 654002MAT2014-59961-C2SEV-2013-0295Liu XMorante JRBeni VVomiero ASolangi AMazzaro RAmin STahira AIbupoto ZHFalhman MfalseA practical non-enzymatic urea sensor based on NiCo₂O₄ nanoneedles.We propose a new facile electrochemical sensing platform for determination of urea, based on a glassy carbon electrode (GCE) modified with nickel cobalt oxide (NiCo₂O₄) nanoneedles. These nanoneedles are used for the first time for highly sensitive determination of urea with the lowest detection limit (1 μM) ever reported for the non-enzymatic approach. The nanoneedles were grown through a simple and low-temperature aqueous chemical method. We characterized the structural and morphological properties of the NiCo₂O₄ nanoneedles by TEM, SEM, XPS and XRD. The bimetallic nickel cobalt oxide exhibits nanoneedle morphology, which results from the self-assembly of nanoparticles. The NiCo₂O₄ nanoneedles are exclusively composed of N2019-01-01T00:00:00Z2019 May2025-04-04T12:43:21.06Z2025-04-04T12:43:21.06ZS-EPMC90641703551933510.1039/c9ra00909d