biostudies-literatureFang GJinan UniversityNational Natural Science Foundation of China20306-20313https://www.ebi.ac.uk/biostudies/studies/S-EPMC9065501biostudies-literatureUnknown9(35)Boronic acid provides faster fluorescence response to Fe³⁺ compared to other reported sensors, which is critical for continuous dynamic detection. Herein, we reported a novel boronic acid-based sensor 4 that could recognize Fe³⁺ ion in real time. After 10 equiv. of Fe³⁺ ion (1 mM) was added, the fluorescence of sensor 4 was immediately quenched by 96%. While other ions, including Ba²⁺, Ca²⁺, Cr²⁺, Cd²⁺, Co²⁺, Cs²⁺, Cu²⁺, Fe²⁺, K⁺, Li⁺, Mg²⁺, Mn²⁺, Na⁺, Ni²⁺ or Zn²⁺, respectively, did not change the fluorescence significantly. Further tests indicated that the high selectively sensing Fe<sup>3+</sRSC advancesA novel boronic acid-based fluorescent sensor for selectively recognizing Fe³⁺ ion in real time.PMC906550121801158JDYY1804Guo MWu ZFang GWang HBian ZYao QfalseA novel boronic acid-based fluorescent sensor for selectively recognizing Fe³⁺ ion in real time.Boronic acid provides faster fluorescence response to Fe³⁺ compared to other reported sensors, which is critical for continuous dynamic detection. Herein, we reported a novel boronic acid-based sensor 4 that could recognize Fe³⁺ ion in real time. After 10 equiv. of Fe³⁺ ion (1 mM) was added, the fluorescence of sensor 4 was immediately quenched by 96%. While other ions, including Ba²⁺, Ca²⁺, Cr²⁺, Cd²⁺, Co²⁺, Cs²⁺, Cu²⁺, Fe²⁺, K⁺, Li⁺, Mg²⁺, Mn²⁺, Na⁺, Ni²⁺ or Zn²⁺, respectively, did not change the fluorescence significantly. Further tests indicated that the high selectively sensing Fe<sup>3+</s2019-01-01T00:00:00Z2019 Jun2025-04-22T07:47:04.496Z2025-04-05T22:19:35.222ZS-EPMC90655013551471210.1039/c9ra03978c