{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Safaei-Ghomi J"],"funding":["University of Kashan"],"pagination":["19662-19674"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9065583"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(34)"],"pubmed_abstract":["We used a novel hybrid catalyst in chemo-, regio-, and diastereoselective multi-component reactions (MCR) for the synthesis of the 2-aza analogue of pyrrolizidine and spirooxindole-2-azapyrrolizidine derivatives. The nanocatalyst, W(iv)/NNBIA-SBA-15 [where NNBIA = <i>N</i>,<i>N</i>'-(ethane-1,2-diyl)bis(2-aminobenzamide)] was synthesized by covalent grafting on chloro-functionalized SBA-15. The synthesis process was followed by the anchoring of WCl<sub>6</sub> to catch the desired catalyst. The quality of the catalyst was assessed using different analytical techniques such as X-ray diffraction spectroscopy (XRD), Fourier-transform infrared spectroscopy (FT-IR), N<sub>2</sub> adsorption analysis, transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM), en"],"journal":["RSC advances"],"pubmed_title":["Tungsten anchored onto functionalized SBA-15: an efficient catalyst for diastereoselective synthesis of 2-azapyrrolizidine alkaloid scaffolds."],"pmcid":["PMC9065583"],"funding_grant_id":["159148/73"],"pubmed_authors":["Bakhtiari A","Safaei-Ghomi J"],"additional_accession":[]},"is_claimable":false,"name":"Tungsten anchored onto functionalized SBA-15: an efficient catalyst for diastereoselective synthesis of 2-azapyrrolizidine alkaloid scaffolds.","description":"We used a novel hybrid catalyst in chemo-, regio-, and diastereoselective multi-component reactions (MCR) for the synthesis of the 2-aza analogue of pyrrolizidine and spirooxindole-2-azapyrrolizidine derivatives. The nanocatalyst, W(iv)/NNBIA-SBA-15 [where NNBIA = <i>N</i>,<i>N</i>'-(ethane-1,2-diyl)bis(2-aminobenzamide)] was synthesized by covalent grafting on chloro-functionalized SBA-15. The synthesis process was followed by the anchoring of WCl<sub>6</sub> to catch the desired catalyst. The quality of the catalyst was assessed using different analytical techniques such as X-ray diffraction spectroscopy (XRD), Fourier-transform infrared spectroscopy (FT-IR), N<sub>2</sub> adsorption analysis, transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM), en","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jun","modification":"2025-04-22T07:47:53.678Z","creation":"2025-04-05T22:18:46.374Z"},"accession":"S-EPMC9065583","cross_references":{"pubmed":["35519375"],"doi":["10.1039/c9ra02825k"]}}