{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(4)"],"submitter":["Liu LJ"],"pubmed_abstract":["<h4>Objective</h4>To investigate the effects of Tongmai Yangxin Pill (TMYXP) combined with metoprolol tartrate or metoprolol alone for the treatment of premature ventricular complex (PVC) in patients with symptomatic frequent PVC.<h4>Methods</h4>A total of 584 patients with symptomatic frequent PVC were randomly assigned (in a 1:1 ratio) into two groups: study group [<i>n</i> = 292, TMYXP (40 pills twice/day, orally) combined with metoprolol tartrate (25 mg twice/day, orally)] and control group [<i>n</i> = 292, metoprolol tartrate (25 mg twice/day, orally) plus placebo pill (40 pills twice/day, orally)]. The total treatment period was eight weeks.<h4>Results</h4>After eight weeks of treatment, the total effective rate of reduction of PVC in the study group and the control group were 76.4% "],"journal":["Journal of geriatric cardiology : JGC"],"pagination":["284-291"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9068592"],"repository":["biostudies-literature"],"pubmed_title":["Tongmai Yangxin Pill combined with metoprolol or metoprolol alone for the treatment of symptomatic premature ventricular complex: a multicenter, randomized, parallel-controlled clinical study."],"pmcid":["PMC9068592"],"pubmed_authors":["Li J","Hua Q","Zhu GH","Sun XP","Liu LJ","Luo HY"],"additional_accession":[]},"is_claimable":false,"name":"Tongmai Yangxin Pill combined with metoprolol or metoprolol alone for the treatment of symptomatic premature ventricular complex: a multicenter, randomized, parallel-controlled clinical study.","description":"<h4>Objective</h4>To investigate the effects of Tongmai Yangxin Pill (TMYXP) combined with metoprolol tartrate or metoprolol alone for the treatment of premature ventricular complex (PVC) in patients with symptomatic frequent PVC.<h4>Methods</h4>A total of 584 patients with symptomatic frequent PVC were randomly assigned (in a 1:1 ratio) into two groups: study group [<i>n</i> = 292, TMYXP (40 pills twice/day, orally) combined with metoprolol tartrate (25 mg twice/day, orally)] and control group [<i>n</i> = 292, metoprolol tartrate (25 mg twice/day, orally) plus placebo pill (40 pills twice/day, orally)]. The total treatment period was eight weeks.<h4>Results</h4>After eight weeks of treatment, the total effective rate of reduction of PVC in the study group and the control group were 76.4% ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-06-01T02:04:29.542Z","creation":"2025-06-01T02:04:29.542Z"},"accession":"S-EPMC9068592","cross_references":{"pubmed":["35572220"],"doi":["10.11909/j.issn.1671-5411.2022.04.008"]}}