biostudies-literatureUnknown19(4)Liu LJ<h4>Objective</h4>To investigate the effects of Tongmai Yangxin Pill (TMYXP) combined with metoprolol tartrate or metoprolol alone for the treatment of premature ventricular complex (PVC) in patients with symptomatic frequent PVC.<h4>Methods</h4>A total of 584 patients with symptomatic frequent PVC were randomly assigned (in a 1:1 ratio) into two groups: study group [<i>n</i> = 292, TMYXP (40 pills twice/day, orally) combined with metoprolol tartrate (25 mg twice/day, orally)] and control group [<i>n</i> = 292, metoprolol tartrate (25 mg twice/day, orally) plus placebo pill (40 pills twice/day, orally)]. The total treatment period was eight weeks.<h4>Results</h4>After eight weeks of treatment, the total effective rate of reduction of PVC in the study group and the control group were 76.4% Journal of geriatric cardiology : JGC284-291https://www.ebi.ac.uk/biostudies/studies/S-EPMC9068592biostudies-literatureTongmai Yangxin Pill combined with metoprolol or metoprolol alone for the treatment of symptomatic premature ventricular complex: a multicenter, randomized, parallel-controlled clinical study.PMC9068592Li JHua QZhu GHSun XPLiu LJLuo HYfalseTongmai Yangxin Pill combined with metoprolol or metoprolol alone for the treatment of symptomatic premature ventricular complex: a multicenter, randomized, parallel-controlled clinical study.<h4>Objective</h4>To investigate the effects of Tongmai Yangxin Pill (TMYXP) combined with metoprolol tartrate or metoprolol alone for the treatment of premature ventricular complex (PVC) in patients with symptomatic frequent PVC.<h4>Methods</h4>A total of 584 patients with symptomatic frequent PVC were randomly assigned (in a 1:1 ratio) into two groups: study group [<i>n</i> = 292, TMYXP (40 pills twice/day, orally) combined with metoprolol tartrate (25 mg twice/day, orally)] and control group [<i>n</i> = 292, metoprolol tartrate (25 mg twice/day, orally) plus placebo pill (40 pills twice/day, orally)]. The total treatment period was eight weeks.<h4>Results</h4>After eight weeks of treatment, the total effective rate of reduction of PVC in the study group and the control group were 76.4% 2022-01-01T00:00:00Z2022 Apr2025-06-01T02:04:29.542Z2025-06-01T02:04:29.542ZS-EPMC90685923557222010.11909/j.issn.1671-5411.2022.04.008