{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Pei MS"],"pubmed_abstract":["Non-conventional peptides (NCPs), which are peptides derived from previously unannotated coding sequences, play important biological roles in plants. In this study, we used peptidogenomic methods that integrated mass spectrometry (MS) peptidomics and a six-frame translation database to extensively identify NCPs in grape. In total, 188 and 2021 non-redundant peptides from the <i>Arabidopsis thaliana</i> and <i>Vitis vinifera</i> L. protein database at Ensembl/URGI and an individualized peptidogenomic database were identified. Unlike conventional peptides, these NCPs derived mainly from intergenic, intronic, upstream ORF, 5'UTR, 3'UTR, and downstream ORF regions. These results show that unannotated regions are translated more broadly than we thought. We also found that most NCPs were derived"],"journal":["Horticulture research"],"pagination":["uhac023"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9070638"],"repository":["biostudies-literature"],"pubmed_title":["Large-scale discovery of non-conventional peptides in grape (<i>Vitis vinifera</i> L.) through peptidogenomics."],"pmcid":["PMC9070638"],"pubmed_authors":["Pei MS","Liu HN","Wei TL","Yu YH","Guo DL"],"additional_accession":[]},"is_claimable":false,"name":"Large-scale discovery of non-conventional peptides in grape (<i>Vitis vinifera</i> L.) through peptidogenomics.","description":"Non-conventional peptides (NCPs), which are peptides derived from previously unannotated coding sequences, play important biological roles in plants. In this study, we used peptidogenomic methods that integrated mass spectrometry (MS) peptidomics and a six-frame translation database to extensively identify NCPs in grape. In total, 188 and 2021 non-redundant peptides from the <i>Arabidopsis thaliana</i> and <i>Vitis vinifera</i> L. protein database at Ensembl/URGI and an individualized peptidogenomic database were identified. Unlike conventional peptides, these NCPs derived mainly from intergenic, intronic, upstream ORF, 5'UTR, 3'UTR, and downstream ORF regions. These results show that unannotated regions are translated more broadly than we thought. We also found that most NCPs were derived","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-04-08T17:49:19.353Z","creation":"2025-02-19T01:23:21.133Z"},"accession":"S-EPMC9070638","cross_references":{"pubmed":["35531313"],"doi":["10.1093/hr/uhac023"]}}