biostudies-literatureXie YFundamental Research Funds for the Central UniversitiesNational Natural Science Foundation of China27904-27910https://www.ebi.ac.uk/biostudies/studies/S-EPMC9071107biostudies-literatureUnknown9(48)In order to reduce the widespread threat of bacterial pathogen diseases, mechanical bactericidal surfaces have been widely reported. However, few of these nanostructured surfaces were investigated from a sustainable perspective. In this study, we have prepared, inspired by the slippery zone of <i>Nepenthes</i>, a multifunctional nanostructured surface with mechanical bactericidal, self-cleaning and insect anti-adhesive characteristics. First, a nanoblade-like surface made of Zn-Al layered double hydroxides was prepared for achieving faster bactericidal rate and wider bactericidal spectrum (2.10 × 10⁴ CFU cm^-2 min^-1 against <i>Escherichia coli</i> and 1.78 × 10³ CFU cm^-2 min^-1 against <i>Staphylococcus aureus</i>). Then the sRSC advances<i>Nepenthes</i>-inspired multifunctional nanoblades with mechanical bactericidal, self-cleaning and insect anti-adhesive characteristics.PMC9071107517722512019XJ02Li JXie YXie XHe XBu DWang LZhou Zfalse<i>Nepenthes</i>-inspired multifunctional nanoblades with mechanical bactericidal, self-cleaning and insect anti-adhesive characteristics.In order to reduce the widespread threat of bacterial pathogen diseases, mechanical bactericidal surfaces have been widely reported. However, few of these nanostructured surfaces were investigated from a sustainable perspective. In this study, we have prepared, inspired by the slippery zone of <i>Nepenthes</i>, a multifunctional nanostructured surface with mechanical bactericidal, self-cleaning and insect anti-adhesive characteristics. First, a nanoblade-like surface made of Zn-Al layered double hydroxides was prepared for achieving faster bactericidal rate and wider bactericidal spectrum (2.10 × 10⁴ CFU cm^-2 min^-1 against <i>Escherichia coli</i> and 1.78 × 10³ CFU cm^-2 min^-1 against <i>Staphylococcus aureus</i>). Then the s2019-01-01T00:00:00Z2019 Sep2025-04-04T23:34:12.691Z2025-04-04T23:34:12.691ZS-EPMC90711073553050110.1039/c9ra05198h