{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Grolimund CM"],"funding":["Schistosomiasis Consortium for Operational Research and Evaluation","European Research Council"],"pagination":["e0010332"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9071146"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(4)"],"pubmed_abstract":["<h4>Background</h4>Reagent strip to detect microhematuria as a proxy for Schistosoma haematobium infections has been considered an alternative to urine filtration for individual diagnosis and community-based estimates of treatment needs for preventive chemotherapy. However, the diagnostic accuracy of reagent strip needs further investigation, particularly at low infection intensity levels.<h4>Methods</h4>We used existing data from a study conducted in Tanzania that employed urine filtration and reagent strip testing for S. haematobium in two villages, including a baseline and six follow-up surveys after praziquantel treatment representing a wide range of infection prevalence. We developed a Bayesian model linking individual S. haematobium egg count data based on urine filtration to reagent"],"journal":["PLoS neglected tropical diseases"],"pubmed_title":["Infection intensity-dependent accuracy of reagent strip for the diagnosis of Schistosoma haematobium and estimation of treatment prevalence thresholds."],"pmcid":["PMC9071146"],"funding_grant_id":["ERC-2012-AdG-323180","323180"],"pubmed_authors":["Barenbold O","Vennervald BJ","Grolimund CM","Mshinda H","Hatz CF","Utzinger J","Mayombana C","Vounatsou P"],"additional_accession":[]},"is_claimable":false,"name":"Infection intensity-dependent accuracy of reagent strip for the diagnosis of Schistosoma haematobium and estimation of treatment prevalence thresholds.","description":"<h4>Background</h4>Reagent strip to detect microhematuria as a proxy for Schistosoma haematobium infections has been considered an alternative to urine filtration for individual diagnosis and community-based estimates of treatment needs for preventive chemotherapy. However, the diagnostic accuracy of reagent strip needs further investigation, particularly at low infection intensity levels.<h4>Methods</h4>We used existing data from a study conducted in Tanzania that employed urine filtration and reagent strip testing for S. haematobium in two villages, including a baseline and six follow-up surveys after praziquantel treatment representing a wide range of infection prevalence. We developed a Bayesian model linking individual S. haematobium egg count data based on urine filtration to reagent","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-18T15:43:49.755Z","creation":"2025-02-19T04:21:28.671Z"},"accession":"S-EPMC9071146","cross_references":{"pubmed":["35468129"],"doi":["10.1371/journal.pntd.0010332"]}}