{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lazow MA"],"funding":["The Gold Hope Project","Reflections Of Grace","Cure Brain Cancer","Ryan’s Hope","Laurie’s Love Foundation","AHRQ HHS","Whitley’s Wishes","Keris Kares","Love Chloe Foundation","Storm the Heavens Fund","The Cure Starts Now Australia","Lily Larue Foundation","The Isabella and Marcus Foundation","Snapgrant.com","The DIPG Collaborative","Pray Hope Believe","Aidan’s Avengers","Wayland Villars Foundation","Marlee’s Mission","RUN DIPG","American Childhood Cancer Organization","Robert Connor Dawes Foundation","the Kyler Strong Foundation","Benny’s World","Aubreigh’s Army","Musella Foundation","Austin Strong","Brooke Healey Foundation","Lauren’s Fight for Cure","Jeffrey Thomas Hayden Foundation","The Cure Starts Now Foundation","Gabriella’s Smile Foundation"],"pagination":["821-833"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9071293"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(5)"],"pubmed_abstract":["<h4>Background</h4>Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment considerations is essential.<h4>Methods</h4>Cases submitted to the International DIPG registry (IDIPGR) with histopathologic and/or radiologic data were analyzed. Central imaging review was performed on diagnostic brain MRIs (if available) by two neuro-radiologists. Imaging features suggestive of alternative diagnoses included nonpontine origin, <50% pontine involvement, focally exophytic morphology, sharply defined margins, and/or marked diffusion restriction throughout.<h4>Results</h4>Among 286 patients with pathology from biopsy and/o"],"journal":["Neuro-oncology"],"pubmed_title":["Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry."],"pmcid":["PMC9071293"],"funding_grant_id":["K12 HS026390"],"pubmed_authors":["Cooney TM","El-Ayadi M","Kilburn L","Sandler ES","Packer R","Fuller C","Wagner LM","Ziegler DS","Gururangan S","Bandopadhayay P","Cheng S","Minturn JE","Zaghloul M","Bartels U","Leary SE","Gottardo N","Monje-Deisseroth M","Lane A","El-Sheikh A","Greiner RJ","Goldman S","Jones BV","Hansford JR","Dholaria H","Leach JL","Dorris K","DeWire M","Cohen KJ","Coven SL","Black K","Bouffet E","Samson Y","Tinkle CL","Fisher PG","Hawkins C","Drissi R","Sevlever G","Garcia Lombardi M","Lazow MA","Fouladi M","Chaney B","Koschmann C","Fonseca A","Hassall T","Ma J","Diez B","Tsui K","Asher A"],"additional_accession":[]},"is_claimable":false,"name":"Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.","description":"<h4>Background</h4>Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment considerations is essential.<h4>Methods</h4>Cases submitted to the International DIPG registry (IDIPGR) with histopathologic and/or radiologic data were analyzed. Central imaging review was performed on diagnostic brain MRIs (if available) by two neuro-radiologists. Imaging features suggestive of alternative diagnoses included nonpontine origin, <50% pontine involvement, focally exophytic morphology, sharply defined margins, and/or marked diffusion restriction throughout.<h4>Results</h4>Among 286 patients with pathology from biopsy and/o","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-04T07:13:31.097Z","creation":"2025-04-04T07:13:31.097Z"},"accession":"S-EPMC9071293","cross_references":{"pubmed":["34668975"],"doi":["10.1093/neuonc/noab245"]}}