biostudies-literatureUnknown9(50)Voß DIn this work we combined kinetic studies for aqueous-phase glucose oxidation in a high-pressure autoclave setup with catalyst reoxidation studies in a liquid-core waveguide membrane reactor. Hereby, we investigated the influence of Nb- and Ta-doping on Mo-based Keggin-polyoxometalates for both reaction steps independently. Most importantly, we could demonstrate a significant increase of glucose oxidation kinetics by Ta- and especially Nb-doping by factors of 1.1 and 1.5 compared to the classical HPA-Mo. Moreover, activation energies for the substrate oxidation step could be significantly reduced from around 80 kJ mol^-1 for the classical HPA-Mo to 61 kJ mol^-1 for the Ta- and 55 kJ mol^-1 for the Nb-doped species, respectively. Regarding catalyst reoxidation kRSC advances29347-29356https://www.ebi.ac.uk/biostudies/studies/S-EPMC9071830biostudies-literatureCombining autoclave and LCWM reactor studies to shed light on the kinetics of glucose oxidation catalyzed by doped molybdenum-based heteropoly acids.PMC9071830Wesinger SAlbert JVoß DPonce SEtzold BJMfalseCombining autoclave and LCWM reactor studies to shed light on the kinetics of glucose oxidation catalyzed by doped molybdenum-based heteropoly acids.In this work we combined kinetic studies for aqueous-phase glucose oxidation in a high-pressure autoclave setup with catalyst reoxidation studies in a liquid-core waveguide membrane reactor. Hereby, we investigated the influence of Nb- and Ta-doping on Mo-based Keggin-polyoxometalates for both reaction steps independently. Most importantly, we could demonstrate a significant increase of glucose oxidation kinetics by Ta- and especially Nb-doping by factors of 1.1 and 1.5 compared to the classical HPA-Mo. Moreover, activation energies for the substrate oxidation step could be significantly reduced from around 80 kJ mol^-1 for the classical HPA-Mo to 61 kJ mol^-1 for the Ta- and 55 kJ mol^-1 for the Nb-doped species, respectively. Regarding catalyst reoxidation k2019-01-01T00:00:00Z2019 Sep2025-04-04T23:17:36.046Z2025-04-04T23:17:36.046ZS-EPMC90718303552839210.1039/c9ra05544d