biostudies-literatureUnknown12Lo CW<h4>Background</h4>The advantage of adjuvant chemotherapy for upper urinary tract urothelial cancer (UTUC) has been reported, whereas its impact on upper tract cancer with variant histology remains unclear. We aimed to answer the abovementioned question with our real-world data.<h4>Design setting and participants</h4>Patients who underwent radical nephroureterectomy (RNU) and were confirmed to have variant UTUC were retrospectively evaluated for eligibility of analysis. In the Taiwan UTUC Collaboration database, we identified 245 patients with variant UTUC among 3,109 patients with UTUC who underwent RNU after excluding patients with missing clinicopathological information.<h4>Intervention</h4>Those patients with variant UTUC were grouped based on their history of receiving adjuvant chemotFrontiers in oncology843715https://www.ebi.ac.uk/biostudies/studies/S-EPMC9072967biostudies-literatureImpact of Adjuvant Chemotherapy on Variant Histology of Upper Tract Urothelial Carcinoma: A Propensity Score-Matched Cohort Analysis.PMC9072967Lin WRChen JSCheong ISChiang BJTseng JSTsai YCChung SDChen CSLin WYHsueh TYYu CCChang YHTsai CYWu HCJou YCKe HLLi WMLee YKChen CHLo CWChen IALin JTChiu AWChen YTHuang CYJiang YHWu CCWeng HYfalseImpact of Adjuvant Chemotherapy on Variant Histology of Upper Tract Urothelial Carcinoma: A Propensity Score-Matched Cohort Analysis.<h4>Background</h4>The advantage of adjuvant chemotherapy for upper urinary tract urothelial cancer (UTUC) has been reported, whereas its impact on upper tract cancer with variant histology remains unclear. We aimed to answer the abovementioned question with our real-world data.<h4>Design setting and participants</h4>Patients who underwent radical nephroureterectomy (RNU) and were confirmed to have variant UTUC were retrospectively evaluated for eligibility of analysis. In the Taiwan UTUC Collaboration database, we identified 245 patients with variant UTUC among 3,109 patients with UTUC who underwent RNU after excluding patients with missing clinicopathological information.<h4>Intervention</h4>Those patients with variant UTUC were grouped based on their history of receiving adjuvant chemot2022-01-01T00:00:00Z20222025-04-04T20:50:29.577Z2025-04-04T20:50:29.577ZS-EPMC90729673553033510.3389/fonc.2022.843715