biostudies-literatureUnknown9(57)Guseva MAA simple one-step approach for the selective synthesis of <i>exo</i>-norbornenes with organosilicon substituents is suggested through the direct hydrosilylation of norbornadiene-2,5 with chlorine-free silanes. Using the example of norbornadiene-2,5 hydrosilylation with pentamethyldisiloxane and 1,1,1,3,5,5,5-heptamethyltrisiloxane, the possibility of obtaining <i>exo</i>-isomers of norbornenes with 100 <i>exo</i>-/<i>endo</i>-selectivity is shown. The investigation of Pt-, Rh-, and Pd-complexes in combination with various ligands as catalysts was performed. The hydrosilylation of norbornadiene-2,5 in the presence of Pt- or Rh-catalysts was not selective and led to a mixture consisting of three isomers (<i>exo</i>-/<i>endo</i>-norbornenes and substituted nortricyclane). In the case of the Pd-salt/ligand catalytic system, the formation of an <i>endo</i>-isomer was not observed at all and only two isomers were formed (<i>exo</i>-norbornene and nortricyclane). The selectivity of <i>exo</i>-norbornene/nortricyclane formation strongly depended on the nature of the ligand in the Pd-catalyst. The best selectivity was revealed when <i>R</i>-MOP was the ligand, while the highest catalytic activity was reached with a dioxalane-containing ligand.RSC advances33029-33037https://www.ebi.ac.uk/biostudies/studies/S-EPMC9073203biostudies-literatureThe selective hydrosilylation of norbornadiene-2,5 by monohydrosiloxanes.PMC9073203Alentiev DABermesheva EVBermeshev MVZamilatskov IAGuseva MAfalseThe selective hydrosilylation of norbornadiene-2,5 by monohydrosiloxanes.A simple one-step approach for the selective synthesis of <i>exo</i>-norbornenes with organosilicon substituents is suggested through the direct hydrosilylation of norbornadiene-2,5 with chlorine-free silanes. Using the example of norbornadiene-2,5 hydrosilylation with pentamethyldisiloxane and 1,1,1,3,5,5,5-heptamethyltrisiloxane, the possibility of obtaining <i>exo</i>-isomers of norbornenes with 100 <i>exo</i>-/<i>endo</i>-selectivity is shown. The investigation of Pt-, Rh-, and Pd-complexes in combination with various ligands as catalysts was performed. The hydrosilylation of norbornadiene-2,5 in the presence of Pt- or Rh-catalysts was not selective and led to a mixture consisting of three isomers (<i>exo</i>-/<i>endo</i>-norbornenes and substituted nortricyclane). In the case of the Pd-salt/ligand catalytic system, the formation of an <i>endo</i>-isomer was not observed at all and only two isomers were formed (<i>exo</i>-norbornene and nortricyclane). The selectivity of <i>exo</i>-norbornene/nortricyclane formation strongly depended on the nature of the ligand in the Pd-catalyst. The best selectivity was revealed when <i>R</i>-MOP was the ligand, while the highest catalytic activity was reached with a dioxalane-containing ligand.2019-01-01T00:00:00Z2019 Oct2025-04-18T15:44:59.033Z2025-02-19T04:21:17.044ZS-EPMC90732033552913010.1039/c9ra06784a