biostudies-literatureAdam MSSDeanship of Scientific Research, King Faisal University34311-34329https://www.ebi.ac.uk/biostudies/studies/S-EPMC9074042biostudies-literatureUnknown9(59)ONO-Pincer Schiff base salicylidene (HSaln ligand) complexes with VO²⁺, UO₂ ²⁺, MoO₂ ²⁺ and Mn²⁺ ions (MSaln complexes = VOSaln, UO₂Saln, MoO₂Saln and MnSaln, respectively) were synthesized and fully characterized by different physico-chemical tools. The VOSaln complex was further treated with 1,10-phenanthroline which afforded a new VO-complex (VOSaln-Ph). All complexes and their ligands, as eco-friendly reagents, were explored for their biological potential as antibacterial and antifungal agents. Reactivity of MSaln complexes against the tested pathogen strains exhibited a remarkable inhibitory effect compared to the coordinated ligand (HSaln) and applicable standard drugs. Moreover, the MSaln complexRSC advancesBiological and catalytic potential of sustainable low and high valent metal-Schiff base sulfonate salicylidene pincer complexes.PMC9074042186121El-Hady OMAdam MSSUllah FfalseBiological and catalytic potential of sustainable low and high valent metal-Schiff base sulfonate salicylidene pincer complexes.ONO-Pincer Schiff base salicylidene (HSaln ligand) complexes with VO²⁺, UO₂ ²⁺, MoO₂ ²⁺ and Mn²⁺ ions (MSaln complexes = VOSaln, UO₂Saln, MoO₂Saln and MnSaln, respectively) were synthesized and fully characterized by different physico-chemical tools. The VOSaln complex was further treated with 1,10-phenanthroline which afforded a new VO-complex (VOSaln-Ph). All complexes and their ligands, as eco-friendly reagents, were explored for their biological potential as antibacterial and antifungal agents. Reactivity of MSaln complexes against the tested pathogen strains exhibited a remarkable inhibitory effect compared to the coordinated ligand (HSaln) and applicable standard drugs. Moreover, the MSaln complex2019-01-01T00:00:00Z2019 Oct2026-05-31T06:00:01.329Z2025-02-19T01:54:34.72ZS-EPMC90740423552996410.1039/c9ra06816c