{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(61)"],"submitter":["Sethuram L"],"pubmed_abstract":["Wound tissue regeneration and angiogenesis are dynamic processes that send physiological signals to the body. Thus, designing novel nanoscaffolds by understanding their surface modifications and toxicological response in a biological system with a potent anti-inflammatory response is a viable solution. In this respect, inspired by the surface chemistry, in the present work we focus on the chemical optimization of silver nanoscaffolds using surface cappings in order to understand their kinetic release behaviour in simulated wound fluids (SWF), to analyze their blood compatibility in human lymphocytes and erythrocytes and then embed them in a chitosan-agarose matrix (CAM) as a productive drug delivery system to evaluate <i>in vivo</i> excision wound tissue regeneration efficiency in Wistar r"],"journal":["RSC advances"],"pagination":["35677-35694"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9074428"],"repository":["biostudies-literature"],"pubmed_title":["Effects and formulation of silver nanoscaffolds on cytotoxicity dependent ion release kinetics towards enhanced excision wound healing patterns in Wistar albino rats."],"pmcid":["PMC9074428"],"pubmed_authors":["Sethuram L","Chandrasekaran N","Mukherjee A","Thomas J"],"additional_accession":[]},"is_claimable":false,"name":"Effects and formulation of silver nanoscaffolds on cytotoxicity dependent ion release kinetics towards enhanced excision wound healing patterns in Wistar albino rats.","description":"Wound tissue regeneration and angiogenesis are dynamic processes that send physiological signals to the body. Thus, designing novel nanoscaffolds by understanding their surface modifications and toxicological response in a biological system with a potent anti-inflammatory response is a viable solution. In this respect, inspired by the surface chemistry, in the present work we focus on the chemical optimization of silver nanoscaffolds using surface cappings in order to understand their kinetic release behaviour in simulated wound fluids (SWF), to analyze their blood compatibility in human lymphocytes and erythrocytes and then embed them in a chitosan-agarose matrix (CAM) as a productive drug delivery system to evaluate <i>in vivo</i> excision wound tissue regeneration efficiency in Wistar r","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Oct","modification":"2025-04-03T21:29:46.673Z","creation":"2025-02-19T01:23:12.718Z"},"accession":"S-EPMC9074428","cross_references":{"pubmed":["35528070"],"doi":["10.1039/c9ra06913e"]}}