biostudies-literatureHan ZNational Basic Research Program of ChinaNatural Science Foundation of Hebei ProvinceNational Natural Science Foundation of ChinaChina Postdoctoral Science Foundation38265-38270https://www.ebi.ac.uk/biostudies/studies/S-EPMC9075902biostudies-literatureUnknown9(65)The green synthesis of palladium nanoparticles (Pd NPs) for catalysis and biological applications has been gaining great interest. To replace complex plant extracts, lentinan (LNT) may be a good reducing and stabilizing agent. In this work, a simple and green method using LNT to reduce and stabilize palladium Pd NPs was verified. The resulting LNT stabilized palladium nanoparticles (Pd _<i>n</i> -LNT NPs) were characterized by UV-Vis spectroscopy, DLS, TEM, and XPS. The results indicated that Pd NPs inside of Pd _<i>n</i> -LNT NPs had a small size (2.35-3.32 nm). Pd _<i>n</i> -LNT NPs were stable in solution for 7 days. In addition, Pd _<i>n</i> -LNT NPs had higher catalytic activity towards the reduction of 4-nitrophenol than other catalysts. More importantly, Pd _<i>n</i> -LNT NPs had negligible cytotoxicity towards cells and showed good antioxidant activity. Taken together, the prepared Pd _<i>n</i> -LNT NPs have great potential bio-related applications.RSC advancesGreen synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications.PMC90759022015CB655303216740922016M601284B20172032292147408521975216Zhang JGuo XDong LHan ZChen SCui TMa GWang LfalseGreen synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications.The green synthesis of palladium nanoparticles (Pd NPs) for catalysis and biological applications has been gaining great interest. To replace complex plant extracts, lentinan (LNT) may be a good reducing and stabilizing agent. In this work, a simple and green method using LNT to reduce and stabilize palladium Pd NPs was verified. The resulting LNT stabilized palladium nanoparticles (Pd _<i>n</i> -LNT NPs) were characterized by UV-Vis spectroscopy, DLS, TEM, and XPS. The results indicated that Pd NPs inside of Pd _<i>n</i> -LNT NPs had a small size (2.35-3.32 nm). Pd _<i>n</i> -LNT NPs were stable in solution for 7 days. In addition, Pd _<i>n</i> -LNT NPs had higher catalytic activity towards the reduction of 4-nitrophenol than other catalysts. More importantly, Pd _<i>n</i> -LNT NPs had negligible cytotoxicity towards cells and showed good antioxidant activity. Taken together, the prepared Pd _<i>n</i> -LNT NPs have great potential bio-related applications.2019-01-01T00:00:00Z2019 Nov2025-04-04T21:32:03.447Z2025-04-04T21:32:03.447ZS-EPMC90759023554177810.1039/c9ra08051a