biostudies-literatureXiao PLanzhou UniversityNatural Science Foundation of ShanghaiNational Natural Science Foundation of China39119-39123https://www.ebi.ac.uk/biostudies/studies/S-EPMC9075993biostudies-literatureUnknown9(67)A sequential cycloaddition and ring expansion of arynes and methylenebenzothiopheneones has been disclosed. This strategy proceeds through a sulfonium ylides intermediate and allows for the efficient synthesis of a sulfur-containing benzo-fused eight-membered ring.RSC advancesSequential cycloaddition and ring expansion reaction of arynes and methylenebenzothiopheneones: synthesis of a benzo-fused eight-membered ring <i>via</i> sulfonium ylides.PMC90759932127214618ZR1413900Xiao PSu SLi JCao WChen JWang WChen YfalseSequential cycloaddition and ring expansion reaction of arynes and methylenebenzothiopheneones: synthesis of a benzo-fused eight-membered ring <i>via</i> sulfonium ylides.A sequential cycloaddition and ring expansion of arynes and methylenebenzothiopheneones has been disclosed. This strategy proceeds through a sulfonium ylides intermediate and allows for the efficient synthesis of a sulfur-containing benzo-fused eight-membered ring.2019-01-01T00:00:00Z2019 Nov2025-04-06T19:46:18.795Z2025-04-06T19:46:18.795ZS-EPMC90759933554065210.1039/c9ra09332j