{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(5)"],"submitter":["Tran CB"],"pubmed_abstract":["An efficient protocol for 8-aminoquinoline assisted alkoxylation and phenoxylation of sp<sup>2</sup> C-H bonds under heterogeneous catalysis was developed. The optimal conditions employed Cu-MOF-74 (20%), K<sub>2</sub>CO<sub>3</sub> base, pyridine ligand or dimethyl formamide solvent, and O<sub>2</sub> oxidant at 80 °C or 100 °C for 24 hours. Cu-MOF-74 revealed remarkably higher activity when compared with other previously commonly used Cu-MOFs in cross coupling reactions, supported copper catalysts, and homogeneous copper salts. The reaction scope with respect to coupling partners included a wide range of various substrates. Interestingly, the developed conditions are applicable for the synthesis of high-profile relevant biological agents from easily accessible starting materials. Further"],"journal":["RSC advances"],"pagination":["2829-2836"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9077472"],"repository":["biostudies-literature"],"pubmed_title":["Auxiliary-directed etherification of sp<sup>2</sup> C-H bonds under heterogeneous metal-organic framework catalysis: synthesis of ethenzamide."],"pmcid":["PMC9077472"],"pubmed_authors":["Cao TTV","Lu HD","Tran CB","Truong T","Duong XNT"],"additional_accession":[]},"is_claimable":false,"name":"Auxiliary-directed etherification of sp<sup>2</sup> C-H bonds under heterogeneous metal-organic framework catalysis: synthesis of ethenzamide.","description":"An efficient protocol for 8-aminoquinoline assisted alkoxylation and phenoxylation of sp<sup>2</sup> C-H bonds under heterogeneous catalysis was developed. The optimal conditions employed Cu-MOF-74 (20%), K<sub>2</sub>CO<sub>3</sub> base, pyridine ligand or dimethyl formamide solvent, and O<sub>2</sub> oxidant at 80 °C or 100 °C for 24 hours. Cu-MOF-74 revealed remarkably higher activity when compared with other previously commonly used Cu-MOFs in cross coupling reactions, supported copper catalysts, and homogeneous copper salts. The reaction scope with respect to coupling partners included a wide range of various substrates. Interestingly, the developed conditions are applicable for the synthesis of high-profile relevant biological agents from easily accessible starting materials. Further","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jan","modification":"2025-04-04T09:10:18.157Z","creation":"2025-02-19T03:24:32.275Z"},"accession":"S-EPMC9077472","cross_references":{"pubmed":["35541499"],"doi":["10.1039/c7ra12010a"]}}