{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(21)"],"submitter":["Zhang H"],"pubmed_abstract":["A novel theranostic prodrug was designed and synthesized by conjugating a naphthalimide derivative with vitamin D<sub>2</sub> <i>via</i> a disulfide linker. The prodrug featured a highly selective detection process for glutathione (GSH) and showed a red-shifted fluorescence within 30 min. Notably, it also exhibited antitumor activity similar to vitamin D<sub>2</sub> and could be monitored by cellular imaging."],"journal":["RSC advances"],"pagination":["11419-11423"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9079131"],"repository":["biostudies-literature"],"pubmed_title":["A novel glutathione-triggered theranostic prodrug for anticancer and imaging in living cells."],"pmcid":["PMC9079131"],"pubmed_authors":["Fang Z","Zhang H"],"additional_accession":[]},"is_claimable":false,"name":"A novel glutathione-triggered theranostic prodrug for anticancer and imaging in living cells.","description":"A novel theranostic prodrug was designed and synthesized by conjugating a naphthalimide derivative with vitamin D<sub>2</sub> <i>via</i> a disulfide linker. The prodrug featured a highly selective detection process for glutathione (GSH) and showed a red-shifted fluorescence within 30 min. Notably, it also exhibited antitumor activity similar to vitamin D<sub>2</sub> and could be monitored by cellular imaging.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2025-04-18T14:14:08.216Z","creation":"2025-02-19T03:25:28.674Z"},"accession":"S-EPMC9079131","cross_references":{"pubmed":["35542771"],"doi":["10.1039/c8ra00271a"]}}