biostudies-literatureUnknown8(34)Singh MCurcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids <i>via</i> a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated <i>via</i> extensive chromatography and characterized by 1D/2D NMR and HRMS analysis.RSC advances18938-18951https://www.ebi.ac.uk/biostudies/studies/S-EPMC9080697biostudies-literatureSynthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids <i>via</i> sequential azomethine ylide cycloaddition.PMC9080697Hazra AGhosh SSahoo ASaha SMondal NBRavichandiran VSingh MKalia RBharitkar YPfalseSynthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids <i>via</i> sequential azomethine ylide cycloaddition.Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids <i>via</i> a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated <i>via</i> extensive chromatography and characterized by 1D/2D NMR and HRMS analysis.2018-01-01T00:00:00Z2018 May2025-04-04T22:49:44.405Z2025-02-19T04:21:25.602ZS-EPMC90806973553965210.1039/c8ra02725k