{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(35)"],"submitter":["Akula PS"],"funding":["Ministry of Science and Technology, Taiwan"],"pubmed_abstract":["A convenient photocatalyzed oxidative coupling reaction of 4-alkyl-3,4-dihydroquinoxalin-2(1<i>H</i>)-one and its derivatives with a variety of nucleophiles was developed with a ruthenium photoredox catalyst and oxygen under a household compact fluorescent light. With a slower reaction rate, the cross coupling transformation can be achieved in the absence of an external photocatalyst with a similar isolated yield. An application to the synthesis of natural product cephalandole A was also demonstrated."],"journal":["RSC advances"],"pagination":["19580-19584"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9080698"],"repository":["biostudies-literature"],"pubmed_title":["Visible-light-induced C(sp<sup>3</sup>)-H activation for a C-C bond forming reaction of 3,4-dihydroquinoxalin-2(1<i>H</i>)-one with nucleophiles using oxygen with a photoredox catalyst or under catalyst-free conditions."],"pmcid":["PMC9080698"],"pubmed_authors":["Lee GH","Hong BC","Akula PS"],"additional_accession":[]},"is_claimable":false,"name":"Visible-light-induced C(sp<sup>3</sup>)-H activation for a C-C bond forming reaction of 3,4-dihydroquinoxalin-2(1<i>H</i>)-one with nucleophiles using oxygen with a photoredox catalyst or under catalyst-free conditions.","description":"A convenient photocatalyzed oxidative coupling reaction of 4-alkyl-3,4-dihydroquinoxalin-2(1<i>H</i>)-one and its derivatives with a variety of nucleophiles was developed with a ruthenium photoredox catalyst and oxygen under a household compact fluorescent light. With a slower reaction rate, the cross coupling transformation can be achieved in the absence of an external photocatalyst with a similar isolated yield. An application to the synthesis of natural product cephalandole A was also demonstrated.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 May","modification":"2025-06-01T02:22:08.43Z","creation":"2024-11-14T19:58:51.406Z"},"accession":"S-EPMC9080698","cross_references":{"pubmed":["35540997"],"doi":["10.1039/c8ra03259a"]}}