biostudies-literatureUnknown8(35)Akula PSMinistry of Science and Technology, TaiwanA convenient photocatalyzed oxidative coupling reaction of 4-alkyl-3,4-dihydroquinoxalin-2(1<i>H</i>)-one and its derivatives with a variety of nucleophiles was developed with a ruthenium photoredox catalyst and oxygen under a household compact fluorescent light. With a slower reaction rate, the cross coupling transformation can be achieved in the absence of an external photocatalyst with a similar isolated yield. An application to the synthesis of natural product cephalandole A was also demonstrated.RSC advances19580-19584https://www.ebi.ac.uk/biostudies/studies/S-EPMC9080698biostudies-literatureVisible-light-induced C(sp³)-H activation for a C-C bond forming reaction of 3,4-dihydroquinoxalin-2(1<i>H</i>)-one with nucleophiles using oxygen with a photoredox catalyst or under catalyst-free conditions.PMC9080698Lee GHHong BCAkula PSfalseVisible-light-induced C(sp³)-H activation for a C-C bond forming reaction of 3,4-dihydroquinoxalin-2(1<i>H</i>)-one with nucleophiles using oxygen with a photoredox catalyst or under catalyst-free conditions.A convenient photocatalyzed oxidative coupling reaction of 4-alkyl-3,4-dihydroquinoxalin-2(1<i>H</i>)-one and its derivatives with a variety of nucleophiles was developed with a ruthenium photoredox catalyst and oxygen under a household compact fluorescent light. With a slower reaction rate, the cross coupling transformation can be achieved in the absence of an external photocatalyst with a similar isolated yield. An application to the synthesis of natural product cephalandole A was also demonstrated.2018-01-01T00:00:00Z2018 May2025-06-01T02:22:08.43Z2024-11-14T19:58:51.406ZS-EPMC90806983554099710.1039/c8ra03259a