{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(38)"],"submitter":["Jakobsson JE"],"pubmed_abstract":["We herein report the development of a convenient, regioselective, aromatic fluorination method of hypervalent iodonium ylides for synthesising fluoro-arenes on a preparative scale. This transition metal free, nucleophilic methodology provides good yields for sterically hindered substrates, irrespective of activation. The methodology simplifies reference synthesis for PET imaging."],"journal":["RSC advances"],"pagination":["21288-21291"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9080924"],"repository":["biostudies-literature"],"pubmed_title":["Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex."],"pmcid":["PMC9080924"],"pubmed_authors":["Riss PJ","Jakobsson JE"],"additional_accession":[]},"is_claimable":false,"name":"Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex.","description":"We herein report the development of a convenient, regioselective, aromatic fluorination method of hypervalent iodonium ylides for synthesising fluoro-arenes on a preparative scale. This transition metal free, nucleophilic methodology provides good yields for sterically hindered substrates, irrespective of activation. The methodology simplifies reference synthesis for PET imaging.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jun","modification":"2025-06-01T02:43:57.734Z","creation":"2025-06-01T02:43:57.734Z"},"accession":"S-EPMC9080924","cross_references":{"pubmed":["35539958"],"doi":["10.1039/c8ra03757d"]}}