biostudies-literatureVillers ANCI NIH HHS333-342https://www.ebi.ac.uk/biostudies/studies/S-EPMC9084627biostudies-literatureUnknown72(3)<h4>Background</h4>Focal ablative therapy may be a suboptimal option for anterior prostate cancers (APCs) reaching the prostate apex due to concerns for thermal injury to the external sphincter.<h4>Objective</h4>To explore the technical feasibility of anterior partial prostatectomy (APP) for isolated APCs detected by magnetic resonance imaging (MRI), and to report short-term oncologic and functional outcomes.<h4>Design, setting, and participants</h4>Following institutional review board approval, over an 8-yr period (2008-2015) 17 consenting patients were enrolled in a prospective single-arm single-center Innovation, Development, Exploration, Assessment, Long-term (IDEAL) phase 2a study. Inclusion criteria comprised preurethral, low- to intermediate-risk APC diagnosed by MRI, and targeted bEuropean urologyPartial Prostatectomy for Anterior Cancer: Short-term Oncologic and Functional Outcomes.PMC9084627P30 CA014089Puech PGill ISLeroy XFlamand VCrouzet SChopra SLemaitre LOuzzane AHaber GPVillers ADesai MMfalsePartial Prostatectomy for Anterior Cancer: Short-term Oncologic and Functional Outcomes.<h4>Background</h4>Focal ablative therapy may be a suboptimal option for anterior prostate cancers (APCs) reaching the prostate apex due to concerns for thermal injury to the external sphincter.<h4>Objective</h4>To explore the technical feasibility of anterior partial prostatectomy (APP) for isolated APCs detected by magnetic resonance imaging (MRI), and to report short-term oncologic and functional outcomes.<h4>Design, setting, and participants</h4>Following institutional review board approval, over an 8-yr period (2008-2015) 17 consenting patients were enrolled in a prospective single-arm single-center Innovation, Development, Exploration, Assessment, Long-term (IDEAL) phase 2a study. Inclusion criteria comprised preurethral, low- to intermediate-risk APC diagnosed by MRI, and targeted b2017-01-01T00:00:00Z2017 Sep2025-04-05T14:42:45.105Z2025-04-05T14:42:45.105ZS-EPMC90846272761306110.1016/j.eururo.2016.08.057