{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shivani S"],"funding":["Ministry of Science and Technology","Yen Tjing Ling Medical Foundation"],"pagination":["726256"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9086402"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12"],"pubmed_abstract":["<h4>Rationale and objective</h4>Gut microbiota have been targeted by alternative therapies for non-communicable diseases. We examined the gut microbiota of a healthy Taiwanese population, identified various bacterial drivers in different demographics, and compared them with dialysis patients to associate kidney disease progression with changes in gut microbiota.<h4>Study design</h4>This was a cross-sectional cohort study.<h4>Settings and participants</h4>Fecal samples were obtained from 119 healthy Taiwanese volunteers, and 16S rRNA sequencing was done on the V3-V4 regions to identify the bacterial enterotypes. Twenty-six samples from the above cohort were compared with fecal samples from 22 peritoneal dialysis and 16 hemodialysis patients to identify species-level bacterial biomarkers in "],"journal":["Frontiers in cellular and infection microbiology"],"pubmed_title":["Uremic Toxin-Producing <i>Bacteroides</i> Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline."],"pmcid":["PMC9086402"],"funding_grant_id":["MOST 108-2321-B-002-031"],"pubmed_authors":["Huang IH","Hsieh YH","Chen JW","Lin WH","Chattopadhyay A","Wang MC","Shivani S","Lai LC","Chuang EY","Lu TP","Kao CY","Teng CH","Tsai MH","Wu JJ"],"additional_accession":[]},"is_claimable":false,"name":"Uremic Toxin-Producing <i>Bacteroides</i> Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline.","description":"<h4>Rationale and objective</h4>Gut microbiota have been targeted by alternative therapies for non-communicable diseases. We examined the gut microbiota of a healthy Taiwanese population, identified various bacterial drivers in different demographics, and compared them with dialysis patients to associate kidney disease progression with changes in gut microbiota.<h4>Study design</h4>This was a cross-sectional cohort study.<h4>Settings and participants</h4>Fecal samples were obtained from 119 healthy Taiwanese volunteers, and 16S rRNA sequencing was done on the V3-V4 regions to identify the bacterial enterotypes. Twenty-six samples from the above cohort were compared with fecal samples from 22 peritoneal dialysis and 16 hemodialysis patients to identify species-level bacterial biomarkers in ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-08-23T03:09:03.146Z","creation":"2024-11-15T01:22:29.778Z"},"accession":"S-EPMC9086402","cross_references":{"pubmed":["35558102"],"doi":["10.3389/fcimb.2022.726256"]}}