biostudies-literatureShivani SMinistry of Science and TechnologyYen Tjing Ling Medical Foundation726256https://www.ebi.ac.uk/biostudies/studies/S-EPMC9086402biostudies-literatureUnknown12<h4>Rationale and objective</h4>Gut microbiota have been targeted by alternative therapies for non-communicable diseases. We examined the gut microbiota of a healthy Taiwanese population, identified various bacterial drivers in different demographics, and compared them with dialysis patients to associate kidney disease progression with changes in gut microbiota.<h4>Study design</h4>This was a cross-sectional cohort study.<h4>Settings and participants</h4>Fecal samples were obtained from 119 healthy Taiwanese volunteers, and 16S rRNA sequencing was done on the V3-V4 regions to identify the bacterial enterotypes. Twenty-six samples from the above cohort were compared with fecal samples from 22 peritoneal dialysis and 16 hemodialysis patients to identify species-level bacterial biomarkers in Frontiers in cellular and infection microbiologyUremic Toxin-Producing <i>Bacteroides</i> Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline.PMC9086402MOST 108-2321-B-002-031Huang IHHsieh YHChen JWLin WHChattopadhyay AWang MCShivani SLai LCChuang EYLu TPKao CYTeng CHTsai MHWu JJfalseUremic Toxin-Producing <i>Bacteroides</i> Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline.<h4>Rationale and objective</h4>Gut microbiota have been targeted by alternative therapies for non-communicable diseases. We examined the gut microbiota of a healthy Taiwanese population, identified various bacterial drivers in different demographics, and compared them with dialysis patients to associate kidney disease progression with changes in gut microbiota.<h4>Study design</h4>This was a cross-sectional cohort study.<h4>Settings and participants</h4>Fecal samples were obtained from 119 healthy Taiwanese volunteers, and 16S rRNA sequencing was done on the V3-V4 regions to identify the bacterial enterotypes. Twenty-six samples from the above cohort were compared with fecal samples from 22 peritoneal dialysis and 16 hemodialysis patients to identify species-level bacterial biomarkers in 2022-01-01T00:00:00Z20222025-08-23T03:09:03.146Z2024-11-15T01:22:29.778ZS-EPMC90864023555810210.3389/fcimb.2022.726256