{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Kuo JY"],"pubmed_abstract":["<h4>Background</h4>Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) commonly coexist with overlapping pathophysiology like left atrial (LA) remodeling, which might differ given different underlying mechanisms.<h4>Objectives</h4>We sought to investigate the different patterns of LA wall remodeling in AF vs. HFpEF.<h4>Methods</h4>We compared LA wall characteristics including wall volume (LAWV), wall thickness (LAWT), and wall thickness heterogeneity (LAWT[SD]) and LA structure, function among the controls (without AF or HFpEF, <i>n</i> = 115), HFpEF alone (<i>n</i> = 59), AF alone (<i>n</i> = 37), and HFpEF+AF (<i>n</i> = 38) groups using multi-detector computed tomography and echocardiography.<h4>Results</h4>LA wall remodeling was most predominant and peak"],"journal":["Frontiers in cardiovascular medicine"],"pagination":["857360"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9086706"],"repository":["biostudies-literature"],"pubmed_title":["Insights on Distinct Left Atrial Remodeling Between Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction."],"pmcid":["PMC9086706"],"pubmed_authors":["Chang SC","Jin X","Sun JY","Hung CL","Sung KT","Wu TH","Mok GSP","Chi PC","Yun CH","Yu CH","Kuo JY","Lam CSP","Chang SH","Chung FP","Yeh HI"],"additional_accession":[]},"is_claimable":false,"name":"Insights on Distinct Left Atrial Remodeling Between Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction.","description":"<h4>Background</h4>Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) commonly coexist with overlapping pathophysiology like left atrial (LA) remodeling, which might differ given different underlying mechanisms.<h4>Objectives</h4>We sought to investigate the different patterns of LA wall remodeling in AF vs. HFpEF.<h4>Methods</h4>We compared LA wall characteristics including wall volume (LAWV), wall thickness (LAWT), and wall thickness heterogeneity (LAWT[SD]) and LA structure, function among the controls (without AF or HFpEF, <i>n</i> = 115), HFpEF alone (<i>n</i> = 59), AF alone (<i>n</i> = 37), and HFpEF+AF (<i>n</i> = 38) groups using multi-detector computed tomography and echocardiography.<h4>Results</h4>LA wall remodeling was most predominant and peak","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T07:44:06.888Z","creation":"2025-04-04T07:44:06.888Z"},"accession":"S-EPMC9086706","cross_references":{"pubmed":["35557544"],"doi":["10.3389/fcvm.2022.857360"]}}