{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Prabhakar A"],"funding":["Science and Engineering Research Board","Indian Institute of Technology Bombay","Department of Science and Technology, Ministry of Science and Technology"],"pagination":["35539-35550"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9088425"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(62)"],"pubmed_abstract":["U or C-shaped waveguides, coupled to analyte microchannels, have been shown to be very responsive to evanescent-wave-absorption-based sensing. However, due to only having a single C-bend length, for analyte interaction in earlier devices, there was always an opportunity to advance their evanescent-absorbance sensitivity, by including multiple C-bend structures (interfaced with the analyte microchannel system) in the device design. To achieve this objective, two different types of waveguide probes (having a different orientation of two C-bends), <i>i.e.</i> S-bend and spiral-bend, were theoretically analyzed and further, experimentally tested for their comparative sensitivity to evanescent wave absorption, in this pioneering study. A novel single-step fabrication procedure (using an SU-8 ph"],"journal":["RSC advances"],"pubmed_title":["Investigation of dual-bend serpentine/spiral waveguides coupled to a microchannel system for competent, evanescent-wave-absorption-based, on-chip, biological-/chemical-sensing applications."],"pmcid":["PMC9088425"],"funding_grant_id":["SR/FTP/ETA-0126/2014","DST/TM/WTI/2K15/201"],"pubmed_authors":["Verma D","Mukherji S","Mishra N","Prabhakar A"],"additional_accession":[]},"is_claimable":false,"name":"Investigation of dual-bend serpentine/spiral waveguides coupled to a microchannel system for competent, evanescent-wave-absorption-based, on-chip, biological-/chemical-sensing applications.","description":"U or C-shaped waveguides, coupled to analyte microchannels, have been shown to be very responsive to evanescent-wave-absorption-based sensing. However, due to only having a single C-bend length, for analyte interaction in earlier devices, there was always an opportunity to advance their evanescent-absorbance sensitivity, by including multiple C-bend structures (interfaced with the analyte microchannel system) in the device design. To achieve this objective, two different types of waveguide probes (having a different orientation of two C-bends), <i>i.e.</i> S-bend and spiral-bend, were theoretically analyzed and further, experimentally tested for their comparative sensitivity to evanescent wave absorption, in this pioneering study. A novel single-step fabrication procedure (using an SU-8 ph","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Oct","modification":"2025-04-27T01:09:28.813Z","creation":"2025-04-06T18:03:16.28Z"},"accession":"S-EPMC9088425","cross_references":{"pubmed":["35558001"],"doi":["10.1039/c8ra06527f"]}}