{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Matsushita K"],"funding":["NHLBI NIH HHS"],"pagination":["e2211946"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9099428"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(5)"],"pubmed_abstract":["<h4>Importance</h4>Little is known about the long-term outcomes of mild valvular lesions.<h4>Objective</h4>To examine the associations of 3 major types of valvular lesions (aortic stenosis, trace or mild aortic regurgitation, and trace or mild mitral regurgitation) with risk of cardiovascular mortality, coronary heart disease (CHD), stroke, heart failure, and atrial fibrillation.<h4>Design, setting, and participants</h4>This cohort study analyzed data from the ongoing Atherosclerosis Risk in Communities study and focused on Black participants in the Jackson, Mississippi, site who underwent echocardiography at visit 3 from 1993 to 1995. Data analysis was conducted between April 2021 and February 2022.<h4>Exposures</h4>Three valvular lesions were analyzed: aortic sclerosis, aortic regurgitat"],"journal":["JAMA network open"],"pubmed_title":["Association of Mild Valvular Lesions With Long-term Cardiovascular Outcomes Among Black Adults."],"pmcid":["PMC9099428"],"funding_grant_id":["K24 HL152440","K24 HL148521","HHSN268201700003I","HHSN268201700004I","HHSN268201700005I","K24 HL152008","R01 HL135008","HHSN268201700001I","HHSN268201700002I"],"pubmed_authors":["Kirtane AJ","Coresh J","Rubin J","Shah AM","Selvin E","Gao Y","Fox ER","Solomon SD","Kodali S","Alonso A","Leon MB","Matsushita K"],"additional_accession":[]},"is_claimable":false,"name":"Association of Mild Valvular Lesions With Long-term Cardiovascular Outcomes Among Black Adults.","description":"<h4>Importance</h4>Little is known about the long-term outcomes of mild valvular lesions.<h4>Objective</h4>To examine the associations of 3 major types of valvular lesions (aortic stenosis, trace or mild aortic regurgitation, and trace or mild mitral regurgitation) with risk of cardiovascular mortality, coronary heart disease (CHD), stroke, heart failure, and atrial fibrillation.<h4>Design, setting, and participants</h4>This cohort study analyzed data from the ongoing Atherosclerosis Risk in Communities study and focused on Black participants in the Jackson, Mississippi, site who underwent echocardiography at visit 3 from 1993 to 1995. Data analysis was conducted between April 2021 and February 2022.<h4>Exposures</h4>Three valvular lesions were analyzed: aortic sclerosis, aortic regurgitat","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-21T13:48:27.265Z","creation":"2025-04-21T13:48:27.265Z"},"accession":"S-EPMC9099428","cross_references":{"pubmed":["35552723"],"doi":["10.1001/jamanetworkopen.2022.11946"]}}