{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Caini S"],"funding":["European Union´s Horizon Europe Research and Innovation Programme under Grant Agreement"],"pagination":["5384"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9099553"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(9)"],"pubmed_abstract":["The contribution of children to viral spread in schools is still debated. We conducted a systematic review and meta-analysis of studies to investigate SARS-CoV-2 transmission in the school setting. Literature searches on 15 May 2021 yielded a total of 1088 publications, including screening, contact tracing, and seroprevalence studies. MOOSE guidelines were followed, and data were analyzed using random-effects models. From screening studies involving more than 120,000 subjects, we estimated 0.31% (95% confidence interval (CI) 0.05-0.81) SARS-CoV-2 point prevalence in schools. Contact tracing studies, involving a total of 112,622 contacts of children and adults, showed that onward viral transmission was limited (2.54%, 95% CI 0.76-5.31). Young index cases were found to be 74% significantly l"],"journal":["International journal of environmental research and public health"],"pubmed_title":["SARS-CoV-2 Circulation in the School Setting: A Systematic Review and Meta-Analysis."],"pmcid":["PMC9099553"],"funding_grant_id":["No 101046016 and Fondazione Invernizzi and Fondazione CARIPLO, Chance Project"],"pubmed_authors":["D'Ecclesiis O","Sasso C","Cammarata G","La Vecchia C","Martinoli C","Raimondi S","Bellerba F","Basso A","Caini S","Gandini S"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV-2 Circulation in the School Setting: A Systematic Review and Meta-Analysis.","description":"The contribution of children to viral spread in schools is still debated. We conducted a systematic review and meta-analysis of studies to investigate SARS-CoV-2 transmission in the school setting. Literature searches on 15 May 2021 yielded a total of 1088 publications, including screening, contact tracing, and seroprevalence studies. MOOSE guidelines were followed, and data were analyzed using random-effects models. From screening studies involving more than 120,000 subjects, we estimated 0.31% (95% confidence interval (CI) 0.05-0.81) SARS-CoV-2 point prevalence in schools. Contact tracing studies, involving a total of 112,622 contacts of children and adults, showed that onward viral transmission was limited (2.54%, 95% CI 0.76-5.31). Young index cases were found to be 74% significantly l","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-04T19:41:06.192Z","creation":"2024-11-15T20:42:01.959Z"},"accession":"S-EPMC9099553","cross_references":{"pubmed":["35564779"],"doi":["10.3390/ijerph19095384"]}}