{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(9)"],"submitter":["Strzemski M"],"pubmed_abstract":["The <i>Chelidonium majus</i> plant is rich in biologically active isoquinoline alkaloids. These alkaline polar compounds are isolated from raw materials with the use of acidified water or methanol; next, after alkalisation of the extract, they are extracted using chloroform or dichloromethane. This procedure requires the use of toxic solvents. The present study assessed the possibility of using volatile natural deep eutectic solvents (VNADESs) for the efficient and environmentally friendly extraction of <i>Chelidonium</i> alkaloids. The roots and herb of the plant were subjected three times to extraction with various menthol, thymol, and camphor mixtures and with water and methanol (acidified and nonacidified). It has been shown that alkaloids can be efficiently isolated using menthol-camp"],"journal":["Molecules (Basel, Switzerland)"],"pagination":["2815"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9101032"],"repository":["biostudies-literature"],"pubmed_title":["Effectiveness of Volatile Natural Deep Eutectic Solvents (VNADESs) for the Green Extraction of <i>Chelidonium majus</i> Isoquinoline Alkaloids."],"pmcid":["PMC9101032"],"pubmed_authors":["Krawczyk P","Wojciak M","Dresler S","Skic K","Sowa I","Zaluski D","Podkoscielna B","Verpoorte R","Strzemski M","Zielinska S"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness of Volatile Natural Deep Eutectic Solvents (VNADESs) for the Green Extraction of <i>Chelidonium majus</i> Isoquinoline Alkaloids.","description":"The <i>Chelidonium majus</i> plant is rich in biologically active isoquinoline alkaloids. These alkaline polar compounds are isolated from raw materials with the use of acidified water or methanol; next, after alkalisation of the extract, they are extracted using chloroform or dichloromethane. This procedure requires the use of toxic solvents. The present study assessed the possibility of using volatile natural deep eutectic solvents (VNADESs) for the efficient and environmentally friendly extraction of <i>Chelidonium</i> alkaloids. The roots and herb of the plant were subjected three times to extraction with various menthol, thymol, and camphor mixtures and with water and methanol (acidified and nonacidified). It has been shown that alkaloids can be efficiently isolated using menthol-camp","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-05-29T22:15:16.469Z","creation":"2025-02-19T00:55:52.076Z"},"accession":"S-EPMC9101032","cross_references":{"pubmed":["35566166"],"doi":["10.3390/molecules27092815"]}}